N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE

N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE - Names and Identifiers

Name	BOC-D-3,4-Difluorophe
Synonyms	BOC-D-Phe(3,4-DiF)-OH BOC-D-3,4-Difluorophe boc-d-3,4-difluorophenylalanine BOC-3,4-difluoro-D-phenylalanine 3,4-Difluoro-D-phenylalanine,N-BOCprotected tert-Butoxycarbonyl-D-3,4-difluorophenylalanine N-TERT-BUTOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE N-(tert-Butoxycarbonyl)-3,4-difluoro-D-phenylalanine N-Benzyloxycarbonyl-3-(3,4-difluorophenyl)-D-alanine Boc-D-Phe(3,4-F2)-OH Boc-3,4-Difluoro-D-Phenylalanine N-Boc-3,4-difluoro-D-phenylalanineBoc-D-Phe(3,4-F)-OH N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE Boc-3,4-difluoro-D-phenylalanine Boc-3,4-difluoro-D-Phe-OH (R)-2-(tert-butoxycarbonylamino)-3-(3,4-difluorophenyl)propanoic acid
CAS	205445-51-8

N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE - Physico-chemical Properties

Molecular Formula	C14H17F2NO4
Molar Mass	301.29
Density	1.270±0.06 g/cm3(Predicted)
Melting Point	98-110°C
Boling Point	430.4±45.0 °C(Predicted)
Solubility	soluble in Methanol
Appearance	Powder
Color	Off-white to white
BRN	9210842
pKa	3.79±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Physical and Chemical Properties	Melting point 98-110°C

N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Note	Irritant

N-ALPHA-T-BUTYLOXYCARBONYL-D-3,4-DIFLUOROPHENYLALANINE - Introduction

BOC-D-3,4-Difluorophe is an organic compound with the chemical formula C12H15F2NO4.

Properties: BOC-D-3,4-Difluorophe is a white crystalline solid, soluble in organic solvents such as dimethyl sulfoxide and ethyl acetate, and low solubility in water. It has the characteristics of two fluorine atoms and an alanine residue.

Purpose: BOC-D-3,4-Difluorophe is commonly used in organic synthesis as a reagent for the synthesis of peptides or other drug molecules. It can be used as an amino protecting group to protect the amino acid to control the selectivity of the reaction and enhance the stability.

Preparation Method: The synthesis of BOC-D-3,4-Difluorophe can be achieved by various methods. A commonly used method is based on 3,4-difluorobenzoic acid as the starting material, through the introduction of the protecting group and the chemical reaction of amino acids, and finally the protection group is removed to generate the target product.

Safety information: BOC-D-3,4-Difluorophe should be handled in accordance with laboratory safety operation guidelines. It is a chemical that may have an effect on human health. During handling or handling, wear appropriate personal protective equipment to avoid contact with skin, eyes and inhalation of gases. At the same time, it should be stored in a closed container, away from fire and oxidizing agents. If exposed or ingested, seek medical attention immediately and carry a chemical label.

Last Update：2024-04-09 21:11:58