N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE
N(alpha)-boc-N(epsilon)-fmoc-L-lysine
CAS: 84624-27-1
Molecular Formula: C26H32N2O6
N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE - Names and Identifiers
| Name | N(alpha)-boc-N(epsilon)-fmoc-L-lysine |
| Synonyms | Boc-Lys(Fmoc)-OH BOC-L-LYS(FROM)-OH Boc-L-Lys(Fmoc)-OH N-Boc-N'-Fmoc-L-Lysine N-α-Boc-N-ε-Fmoc-L-lysine N-t-BOC-N-U-FMOC-L-lysine N(alpha)-boc-N(epsilon)-fmoc-L-lysine N-tert-Butoxycarbonyl-Nε-Fmoc-L-lysine NALPHA-tert-Butoxycarbonyl-NEPSILON-9-fluorenylmethoxycarbonyl-L- lysine N~2~-(tert-butoxycarbonyl)-N~6~-[(9H-fluoren-9-ylmethoxy)carbonyl]lysine N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE 6-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-(tert-butoxycarbonylamino)hexanoic acid |
| CAS | 84624-27-1 |
| InChI | InChI=1/C26H32N2O6/c1-26(2,3)34-25(32)28-22(23(29)30)14-8-9-15-27-24(31)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30) |
N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE - Physico-chemical Properties
| Molecular Formula | C26H32N2O6 |
| Molar Mass | 468.54 |
| Density | 1.210±0.06 g/cm3(Predicted) |
| Melting Point | 93-98℃ |
| Boling Point | 685.7±55.0 °C(Predicted) |
| Specific Rotation(α) | 3.3 º (c=1% in ethyl acetate) |
| Flash Point | 368.5°C |
| Water Solubility | Soluble in dimethylformamide. Insoluble in water. |
| Vapor Presure | 9.55E-20mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | 3.99±0.21(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.566 |
N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE - Risk and Safety
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
N-ALPHA-T-BUTYLOXYCARBONYL-N-EPSILON-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LYSINE - Introduction
N(alpha)-boc-N(epsilon)-fmoc-L-lysine is an amino acid derivative with the following properties:
Nature:
-Appearance: colorless crystal or solid
-Molecular formula: C44H52N2O11
-Molecular Weight: 800.89
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO), dimethyl formamide (DMF), etc.
Use:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine can be used in solid phase synthesis (peptide synthesis) as the starting or terminal amino acid of a synthetic polypeptide chain.
-In the synthesis process, its BOC protecting group and FMOC protecting group can provide chemical stability and protect the amino acid from the interference of the external environment.
Preparation Method:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine synthesis method is more complex, usually including multi-step organic synthesis reaction.
-A commonly used synthesis method is to protect the amino group (NH2) and ε-carboxyl group (COOH) of lysine with BOC and FMOC respectively to obtain the desired product.
Safety Information:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine is a chemical reagent that needs to be operated under appropriate laboratory conditions.
-During use, safe practices should be followed, including wearing appropriate personal protective equipment (e. g. gloves, goggles) to reduce the risk of exposure.
-Waste should be disposed of in accordance with relevant regulations to avoid environmental pollution.
Nature:
-Appearance: colorless crystal or solid
-Molecular formula: C44H52N2O11
-Molecular Weight: 800.89
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO), dimethyl formamide (DMF), etc.
Use:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine can be used in solid phase synthesis (peptide synthesis) as the starting or terminal amino acid of a synthetic polypeptide chain.
-In the synthesis process, its BOC protecting group and FMOC protecting group can provide chemical stability and protect the amino acid from the interference of the external environment.
Preparation Method:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine synthesis method is more complex, usually including multi-step organic synthesis reaction.
-A commonly used synthesis method is to protect the amino group (NH2) and ε-carboxyl group (COOH) of lysine with BOC and FMOC respectively to obtain the desired product.
Safety Information:
- N(alpha)-boc-N(epsilon)-fmoc-L-lysine is a chemical reagent that needs to be operated under appropriate laboratory conditions.
-During use, safe practices should be followed, including wearing appropriate personal protective equipment (e. g. gloves, goggles) to reduce the risk of exposure.
-Waste should be disposed of in accordance with relevant regulations to avoid environmental pollution.
Last Update：2024-04-10 22:29:15
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CAS: 84624-27-1
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