N-Acetyl-3-indolinone
1-Acetyl-3-indolinone
CAS: 16800-68-3
Molecular Formula: C10H9NO2
N-Acetyl-3-indolinone - Names and Identifiers
| Name | 1-Acetyl-3-indolinone |
| Synonyms | AKOS UB-20202 N-ACETYLINDOXYL IFLAB-BB F1011-0534 1-ACETYL-3-INDOLINONE N-Acetyl-3-indolinone 1-Acetyl-3-indolinone 1-Acetyl-1,2-dihydroindol-3-one 1-ACETYL-1,2-DIHYDRO-INDOL-3-ONE 1-acetyl-1,2-dihydro-3H-indol-3-one 1-Acetyl-1,2-dihydro-3H-indol-3-one 3H-Indol-3-one, 1-acetyl-1,2-dihydro- |
| CAS | 16800-68-3 |
| InChI | InChI=1/C10H9NO2/c1-7(12)11-6-10(13)8-4-2-3-5-9(8)11/h2-5H,6H2,1H3 |
N-Acetyl-3-indolinone - Physico-chemical Properties
| Molecular Formula | C10H9NO2 |
| Molar Mass | 175.18 |
| Density | 1.275±0.06 g/cm3(Predicted) |
| Melting Point | 133-134 °C(Solv: ethanol (64-17-5); water (7732-18-5)) |
| Boling Point | 411.2±34.0 °C(Predicted) |
| Flash Point | 211.2°C |
| Vapor Presure | 5.68E-07mmHg at 25°C |
| pKa | -1.85±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.595 |
N-Acetyl-3-indolinone - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R43 - May cause sensitization by skin contact |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| Hazard Class | IRRITANT |
N-Acetyl-3-indolinone - Introduction
1-Acetyl-3-indolinone, also known as 1-acetoindol-3-one, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1-Acetyl-3-indolinone is in the form of white crystals or crystalline powders, with special ketone and pyrrole ring structures. Its chemical formula is C10H9NO2 and its molecular weight is 175.18g/mol. It has good solubility at room temperature and can be dissolved in some organic solvents, such as ethanol and dimethyl sulfoxide.
Use:
1-Acetyl-3-indolinone is often used as an intermediate or reagent in organic synthesis. It is often used in the pharmaceutical field to synthesize a variety of biologically active compounds, such as anticancer drugs, antiviral drugs and antibacterial drugs. In addition, it can also be used as a raw material for dyes and photosensitizers.
Method:
1-Acetyl-3-indolinone can be prepared in a variety of ways. A common preparation method is obtained by reacting 3-indolinone with acetyl chloride. The reaction is usually carried out in the presence of sodium chloride, and the reaction product is crystallized under appropriate conditions to obtain the target compound.
Safety Information:
Safety information about 1-Acetyl-3-indolinone is rarely reported, but in general, appropriate precautions are required for the use and handling of any chemical substance. It may be irritating to the eyes and skin, so during operation, it is necessary to wear appropriate protective equipment, such as goggles, gloves and laboratory clothing. In addition, during storage and handling, it is necessary to comply with relevant safety procedures.
Nature:
1-Acetyl-3-indolinone is in the form of white crystals or crystalline powders, with special ketone and pyrrole ring structures. Its chemical formula is C10H9NO2 and its molecular weight is 175.18g/mol. It has good solubility at room temperature and can be dissolved in some organic solvents, such as ethanol and dimethyl sulfoxide.
Use:
1-Acetyl-3-indolinone is often used as an intermediate or reagent in organic synthesis. It is often used in the pharmaceutical field to synthesize a variety of biologically active compounds, such as anticancer drugs, antiviral drugs and antibacterial drugs. In addition, it can also be used as a raw material for dyes and photosensitizers.
Method:
1-Acetyl-3-indolinone can be prepared in a variety of ways. A common preparation method is obtained by reacting 3-indolinone with acetyl chloride. The reaction is usually carried out in the presence of sodium chloride, and the reaction product is crystallized under appropriate conditions to obtain the target compound.
Safety Information:
Safety information about 1-Acetyl-3-indolinone is rarely reported, but in general, appropriate precautions are required for the use and handling of any chemical substance. It may be irritating to the eyes and skin, so during operation, it is necessary to wear appropriate protective equipment, such as goggles, gloves and laboratory clothing. In addition, during storage and handling, it is necessary to comply with relevant safety procedures.
Last Update：2024-04-09 20:52:54
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Product Name: 1-Acetyl-3-indolinone Visit Supplier Webpage Request for quotationCAS: 16800-68-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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