N-Acetylcysteamine - Names and Identifiers
Name | N-acetylcysteamine
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Synonyms | NSC 38835 BRN 1743117 Acetylcysteamine N-acetylcysteamine N-Acetylcysteamine N-Acetyl cysteamin N-Acetyl cysteamine Cysteamine,N-acetyl Cysteamine, N-acetyl- 2-Acetamidoethanethiol N-Acetylmercaptoethylamine 2-(acetylamino)-ethanethio N-Acetyl cysteamin [German] N-(2-sulfanylethyl)acetamide N-(2-Mercaptoethyl)acetamide Ethanethiol, 2-(acetylamino)- Acetamide, N-(2-mercaptoethyl)- Acetamide, N-(beta-mercaptoethyl)- Acetamide, N-(2-mercaptoethyl)- (8CI,9CI) 4-04-00-01607 (Beilstein Handbook Reference) PS-5 IMPURITY 1 (N-(2-SULFANYLETHYL)ACETAMIDE) N-Acetylcysteamine,N-(2-Mercaptoethyl)acetamide
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CAS | 1190-73-4
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InChI | InChI=1/C4H9NOS/c1-4(6)5-2-3-7/h7H,2-3H2,1H3,(H,5,6) |
N-Acetylcysteamine - Physico-chemical Properties
Molecular Formula | C4H9NOS
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Molar Mass | 119.19 |
Density | 1.121 g/mL at 25 °C (lit.) |
Melting Point | 6-7 °C (lit.) |
Boling Point | 138-140 °C/7 mmHg (lit.) |
Flash Point | >230°F |
Solubility | Ether; Dichloromethane; Ethyl Acetate; Methanol |
Vapor Presure | 0.00289mmHg at 25°C |
Appearance | liquid |
Color | Clear |
pKa | 9.92±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | n20/D 1.511(lit.) |
N-Acetylcysteamine - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
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WGK Germany | 3 |
RTECS | AC4620000 |
N-Acetylcysteamine - Introduction
N-acetylcysteamine is an organic compound with the chemical formula C5H9N3O2S. The following is a description of the properties, uses, preparation and safety information of N-acetylcysteamine:
Nature:
N-acetylcysteamine is a colorless crystalline solid that is soluble in water and acidic in solution. It has good stability, heat resistance, humidity resistance and light resistance.
Use:
N-acetylcysteamine is primarily used as a photoprotective agent in cosmetics and personal care products. It can reverse the skin oxidation and photoaging caused by ultraviolet rays and effectively protect the skin from ultraviolet rays. In addition, N-acetylcysteamine is also used in the medical field, as an antioxidant and active substance in the preparation of some drugs.
Preparation Method:
N-acetylcysteamine is generally prepared by reacting thiocyanic acid with acetaldehyde. The specific preparation method is to react thiocyanic acid with acetaldehyde under the catalysis of alkali to generate N-acetyl cysteamine, and obtain pure products through crystallization or other separation methods.
Safety Information:
N-acetylcysteamine is relatively safe under normal use conditions, and has no obvious toxicity and irritation. However, as a chemical substance, it is still necessary to comply with the basic rules of safe operation. During use, avoid contact with eyes, skin or inhalation of its dust. If accidental contact occurs, rinse immediately with plenty of water. At the same time, the relevant industrial hygiene and safety regulations should be followed and stored in a dry, well-ventilated place.
Last Update:2024-04-09 21:11:58