N-Acetylphenethylamine - Names and Identifiers
N-Acetylphenethylamine - Physico-chemical Properties
Molecular Formula | C10H13NO
|
Molar Mass | 163.22 |
Density | 1.012 |
Melting Point | 48-52 °C |
Boling Point | 154 °C / 2mmHg |
Flash Point | 204°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Vapor Presure | 5.69E-05mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 16.17±0.46(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.5400 (estimate) |
MDL | MFCD00026177 |
N-Acetylphenethylamine - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
RTECS | AC7740000 |
HS Code | 29241900 |
N-Acetylphenethylamine - Introduction
N-(2-phenylethyl)acetamide(N-(2-phenylethyl)acetamide) is an organic compound with the following properties and uses:
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C10H13NO
-Molecular weight: 163.22g/mol
-Melting Point: 58-62°C
-Boiling point: 294°C
-Solubility: Soluble in polar solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
-Pharmaceutical field: N-(2-phenylethyl)acetamide are often used as intermediates for the synthesis of drugs and bioactive molecules. It is used as a raw material for anticancer drugs, bioactive agents and transdermal drug delivery agents.
Preparation Method:
The preparation method of N-(2-phenylethyl)acetamide can be achieved in a variety of ways, one of which is a common method through the following steps:
1. take acetophenone as a starting material and react with bromoacetic acid to form N-bromoacyl -2-phenylethylamine.
2. Next, N-bromoacyl-2-phenylethylamine is reacted with ammonia to produce N-(2-phenylethyl)acetamide.
3. Finally, the target product is obtained by crystallization or other purification methods.
Safety Information:
N-(2-phenylethyl)acetamide related safety information lack of clear reporting and evaluation. However, as a general guideline when handling chemicals, the following safety precautions should be observed when using:
-Avoid contact with skin, eyes and taking. In case of contact, rinse immediately with plenty of water.
-Appropriate protective measures, such as laboratory gloves and safety glasses, should be used during operation.
-When used in a laboratory environment, follow appropriate safety practices and laboratory regulations.
-Before use, you should carefully read and understand the relevant material safety data sheets (MSDS) that affect health and safety.
Last Update:2024-04-09 21:00:56