Name | N-Acetyl-L-carnosine |
Synonyms | UNII-0TPN86OQIF N-Acetyl camosine N-Acetylcarnosine n-acetyl carnosine N-Acetyl Carnosine N-Aceyl-L-Carnosine N-ACETYL-L-CARNOSINE CARNOSINE IMPURITY 4 N-Acetyl-L-carnosine N-acetyl-beta-alanylhistidine N-acetyl-beta-alanyl-L-histidine N-A-ACETYL-N-B-ALANYL-L-HISTIDINE N-(N-acetyl-beta-alanyl)-L-histidine N-(N-Acetyl-beta-alanyl)-L-histidine NAC, N-a-Acetyl-N-b-alanyl-L-histidine (S)-2-(3-ACETYLAMINO-PROPIONYLAMINO)-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID |
CAS | 56353-15-2 56353-23-0 |
EINECS | 260-123-2 |
InChI | InChI=1/C11H16N4O4/c1-7(16)13-3-2-10(17)15-9(11(18)19)4-8-5-12-6-14-8/h5-6,9H,2-4H2,1H3,(H,12,14)(H,13,16)(H,15,17)(H,18,19)/t9-/m0/s1 |
Molecular Formula | C11H16N4O4 |
Molar Mass | 268.27 |
Density | 1.343±0.06 g/cm3(Predicted) |
Melting Point | 209-210°C |
Boling Point | 775.9±60.0 °C(Predicted) |
Flash Point | 423.021°C |
Solubility | Methanol (Slightly), Water (Slightly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 3.08±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.563 |
In vivo study | Right eyes of the rabbits (male grey chinchilla rabbits aged 3-4 months weighing 2-3 k) are instilled with 80 μL of formulation A containing 1 % N-Acetylcarnosine. The N-Acetylcarnosine prodrug eye drops optimize the clinical effects for the treatment of ophthalmic disorders (such as prevention and reversal of cataracts in human and animal eyes). |
biological activity | N-Acetylcarnosine is a natural, histidine-containing dipeptide, it is the pharmacologically predominant L-carnosine source. N-Acetylcarnosine is an effective ophthalmic drug with potential for use in human cataracts. |