N-BETA-T-BUTOXYCARBONYL-N-OMEGA-(P-TOLUENESULFONYL)-L-BETA-HOMOARGININE - Names and Identifiers
Name | BOC-L-BETA-HOMOARGININE(TOS)
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Synonyms | -HoArg(Tos)-OH Boc-β-HoArg(Tos)-OH BOC-BETA-HOARG(TOS)-OH BOC-ARG(TOS)-(C*CH2)OH BOC-BETA-HOMOARG(TOS)-OH BOC-L-BETA-HOMOARGININE(TOS) BOC-N-OMEGA-TOSYL-L-BETA-HOMOARGININE N-BETA-BOC-N-OMEGA-TOSYL-BETA-HOMOARGININE N-BETA-BOC-N-OMEGA-TOSYL-L-BETA-HOMOARGININE N-BETA-T-BUTOXYCARBONYL-N-OMEGA-(P-TOLUENESULFONYL)-L-BETA-HOMOARGININE (3S)-6-{[(1E)-amino{[(4-methylphenyl)sulfonyl]amino}methylidene]amino}-3-[(tert-butoxycarbonyl)amino]hexanoic acid
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CAS | 136271-81-3
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InChI | InChI=1/C19H30N4O6S/c1-13-7-9-15(10-8-13)30(27,28)23-17(20)21-11-5-6-14(12-16(24)25)22-18(26)29-19(2,3)4/h7-10,14H,5-6,11-12H2,1-4H3,(H,22,26)(H,24,25)(H3,20,21,23)/t14-/m0/s1 |
N-BETA-T-BUTOXYCARBONYL-N-OMEGA-(P-TOLUENESULFONYL)-L-BETA-HOMOARGININE - Physico-chemical Properties
Molecular Formula | C19H30N4O6S
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Molar Mass | 442.53 |
Density | 1.29g/cm3 |
Storage Condition | 2-8°C |
Refractive Index | 1.571 |
MDL | MFCD03427576 |
Physical and Chemical Properties | WGK Germany:3 |
N-BETA-T-BUTOXYCARBONYL-N-OMEGA-(P-TOLUENESULFONYL)-L-BETA-HOMOARGININE - Risk and Safety
WGK Germany | 3 |
Hazard Class | IRRITANT |
N-BETA-T-BUTOXYCARBONYL-N-OMEGA-(P-TOLUENESULFONYL)-L-BETA-HOMOARGININE - Introduction
Boc-L-β-homoarginine is an organic compound, all of which is known as a calcium. It is an amino acid derivative with a protecting group, where Boc is an abbreviation for tert-butoxycarbonyl, which is used to protect the amino group. The properties of Boc-L-β-homoarginine p-toluenesulfonate are mainly reflected in solubility and stability.
Boc-L-β-homoarginine p-toluenesulfonate is insoluble in water and soluble in some organic solvents, such as dimethyl sulfoxide. It is stable at room temperature, but may undergo hydrolysis under acidic conditions. In addition, Boc-L-β-homoarginine p-toluenesulfonate also needs to be protected from exposure to air during storage and use to prevent reaction with water vapor or carbon dioxide.
One of the main uses of Boc-L-β-homoarginine p-toluenesulfonate is its application as an amino acid protecting group in organic synthesis. It can be used in the synthesis of polypeptides and proteins in which the protective group acts to protect the amino group during the reaction to prevent unnecessary reactions. In addition, Boc-L-β-homoarginine p-toluenesulfonate can also be used in drug synthesis and biochemical studies.
Boc-L-β-homoarginine p-toluenesulfonate is usually prepared by synthesis. A common synthetic method is to react homoarginine with Boc-OSu(tert-Butyloxycarbonyl-OSu) in a suitable solvent to form Boc-L-β-homoarginine p-toluenesulfonate. After successful synthesis, the pure product can be obtained by proper operation.
When using and storing Boc-L-β-homoarginine p-toluenesulfonate, it is necessary to follow the appropriate safety guidelines. Wear appropriate personal protective equipment, such as lab gloves and safety glasses, to avoid skin contact. In addition, it should be stored in a dry, cool and well-ventilated place, away from fire and oxidizing agents. In the process to avoid inhalation of dust or solution, avoid eating and drinking water. In case of accidental contact, rinse immediately with plenty of water and seek medical attention immediately.
Last Update:2024-04-09 20:52:54