N-BOC-D-PROLINOL
Boc-D-prolinol
CAS: 83435-58-9
Molecular Formula: C10H19NO3
N-BOC-D-PROLINOL - Names and Identifiers
| Name | Boc-D-prolinol |
| Synonyms | BOC-D-PRO-OL BOC-D-PROLINOL Boc-D-prolinol N-BOC-D-PROLINOL N-T-BOC-D-PROLINOL N-ALPHA-T-BOC-D-PROLINOL N-T-BUTOXYCARBONYL-D-PROLINOL N-TERT-BUTOXYCARBONYL-D-PROLINOL BOC-(R)-2-(HYDROXYMETHYL) PYRROLIDINE |
| CAS | 83435-58-9 |
| EINECS | 626-169-6 |
| InChIKey | BFFLLBPMZCIGRM-MRVPVSSYSA-N |
N-BOC-D-PROLINOL - Physico-chemical Properties
| Molecular Formula | C10H19NO3 |
| Molar Mass | 201.26 |
| Density | 1.084±0.06 g/cm3(Predicted) |
| Melting Point | 60-64 °C (lit.) |
| Boling Point | 289.5±13.0 °C(Predicted) |
| Specific Rotation(α) | 49 º (589nm, =1.3, CHCl3) |
| Water Solubility | insoluble |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | White solid |
| Color | White to light beige |
| pKa | 14.77±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 54 ° (C=5, MeOH) |
| MDL | MFCD00040580 |
| Physical and Chemical Properties | White solid |
N-BOC-D-PROLINOL - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29051990 |
N-BOC-D-PROLINOL - Introduction
Boc-D-prolinol(Boc-D-prolinol) is an organic compound with a chemical formula of C12H22N2O3 and a molecular weight of 242.32g/mol. It is a white crystalline solid, stable at room temperature.
Boc-D-prolinol is often used as a chiral reagent in organic synthesis. It can be used in the synthesis of compounds with a proline chiral backbone, such as drugs, polypeptides and natural products. The chiral nature of the compound makes it very sensitive to optical activity and can be used to synthesize target compounds with specific optical activity.
The preparation of Boc-D-prolinol generally involves reacting allyl alcohol, the protecting group of which is Boc(tert-butoxycarbonyl), with D-proline to produce the desired product, Boc-D-prolinol. Detailed descriptions of specific preparation methods can be found in the literature or patents.
Regarding safety information, Boc-D-prolinol is relatively safe under normal laboratory conditions, it still needs to be handled with caution. Because it is soluble in organic solvents and is irritating to the eyes and skin, it is necessary to wear appropriate protective equipment, such as gloves and safety glasses. In addition, the storage and handling of chemicals should follow the relevant safety regulations. If the use of this compound is required, please refer to the specific Safety Data Sheet (SDS) for more detailed safety information.
Boc-D-prolinol is often used as a chiral reagent in organic synthesis. It can be used in the synthesis of compounds with a proline chiral backbone, such as drugs, polypeptides and natural products. The chiral nature of the compound makes it very sensitive to optical activity and can be used to synthesize target compounds with specific optical activity.
The preparation of Boc-D-prolinol generally involves reacting allyl alcohol, the protecting group of which is Boc(tert-butoxycarbonyl), with D-proline to produce the desired product, Boc-D-prolinol. Detailed descriptions of specific preparation methods can be found in the literature or patents.
Regarding safety information, Boc-D-prolinol is relatively safe under normal laboratory conditions, it still needs to be handled with caution. Because it is soluble in organic solvents and is irritating to the eyes and skin, it is necessary to wear appropriate protective equipment, such as gloves and safety glasses. In addition, the storage and handling of chemicals should follow the relevant safety regulations. If the use of this compound is required, please refer to the specific Safety Data Sheet (SDS) for more detailed safety information.
Last Update：2024-04-09 21:04:16
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