N-BOC-O-甲基-L-苏氨酸
Boc-O-methyl-L-threonine
CAS: 48068-25-3
Molecular Formula: C10H19NO5
N-BOC-O-甲基-L-苏氨酸 - Names and Identifiers
| Name | Boc-O-methyl-L-threonine |
| Synonyms | BOC-THR(ME) Boc-Thr(Me)-OH BOC-THR(ME)-OH Boc-L-Thr(Me)-OH Boc-O-methyl-L-threonine BOC-O-METHYL-L-THREONINE (Tert-Butoxy)Carbonyl Thr(Me)-OH O-Methyl-L-threonine, N-BOC protected (2S,3R)-2-(tert-butoxycarbonylamino)-3-methoxybutanoic acid (2S,3R)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid |
| CAS | 48068-25-3 |
| InChI | InChI=1/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6?,7-/m0/s1 |
N-BOC-O-甲基-L-苏氨酸 - Physico-chemical Properties
| Molecular Formula | C10H19NO5 |
| Molar Mass | 233.26 |
| Density | 1.123±0.06 g/cm3(Predicted) |
| Boling Point | 362.1±37.0 °C(Predicted) |
| Appearance | Solid |
| pKa | 3.50±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.46 |
| MDL | MFCD00076990 |
N-BOC-O-甲基-L-苏氨酸 - Introduction
Boc-O-methyl-L-threonine is an amino acid derivative, and Boc in its chemical structure represents a protecting group, which protects the amino functional group on the amino group, so that it is not easy to be attacked by reactants, which is conducive to subsequent chemical synthesis.
The properties of Boc-O-methyl-L-threonine mainly include physical properties and chemical properties. Physically, it is a white crystalline solid, stable at room temperature. The solubility in water is low, but it is soluble in organic solvents such as methanol, ethanol and dichloromethane. Chemically, it is an optically active compound with the characteristics of reactivity and availability for chemical modification.
Boc-O-methyl-L-threonine have a variety of uses in the field of chemical synthesis. First, it can be used as an amino acid protecting group to protect other functional groups during polypeptide or protein synthesis, allowing selective reactions to occur. Secondly, it can be used in organic synthesis reactions, as an amine source or amino acid derivatives to participate in the reaction to generate new organic compounds.
The method of preparing Boc-O-methyl-L-threonine is generally carried out by means of chemical synthesis. A specific preparation method may be to react Boc-threonine with methanol to introduce a methyl group into the amino group of threonine. In addition, the Boc-O-methyl-L-threonine can also be obtained by other methods, such as protection of the thiol group of the amino acid and subsequent methylation reaction.
For safety information, Boc-O-methyl-L-threonine are generally stable and low toxicity compounds. However, it is still necessary to pay attention to some basic safety operation specifications, avoid direct contact with skin and eyes during operation, and avoid inhaling dust or gas. Avoid contact with oxidants or other chemicals during storage and use, and store in a dry and ventilated place.
The properties of Boc-O-methyl-L-threonine mainly include physical properties and chemical properties. Physically, it is a white crystalline solid, stable at room temperature. The solubility in water is low, but it is soluble in organic solvents such as methanol, ethanol and dichloromethane. Chemically, it is an optically active compound with the characteristics of reactivity and availability for chemical modification.
Boc-O-methyl-L-threonine have a variety of uses in the field of chemical synthesis. First, it can be used as an amino acid protecting group to protect other functional groups during polypeptide or protein synthesis, allowing selective reactions to occur. Secondly, it can be used in organic synthesis reactions, as an amine source or amino acid derivatives to participate in the reaction to generate new organic compounds.
The method of preparing Boc-O-methyl-L-threonine is generally carried out by means of chemical synthesis. A specific preparation method may be to react Boc-threonine with methanol to introduce a methyl group into the amino group of threonine. In addition, the Boc-O-methyl-L-threonine can also be obtained by other methods, such as protection of the thiol group of the amino acid and subsequent methylation reaction.
For safety information, Boc-O-methyl-L-threonine are generally stable and low toxicity compounds. However, it is still necessary to pay attention to some basic safety operation specifications, avoid direct contact with skin and eyes during operation, and avoid inhaling dust or gas. Avoid contact with oxidants or other chemicals during storage and use, and store in a dry and ventilated place.
Last Update：2024-04-09 21:01:54
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