N-Benzyl-4-Amino-Piperidine-4-Carboxamide

N-Benzyl-4-Amino-Piperidine-4-Carboxamide - Names and Identifiers

Name	N-Benzyl-4-Amino-Piperidine-4-Carboxamide
Synonyms	4-Amino-1-benzylpiperidine-4-carboxamide 4-AMino-N-benzylpiperidine-4-carboxaMide N-BENZYL-4-AMINO-PIPERIDINE-4-CARBOXAMIDE N-Benzyl-4-Amino-Piperidine-4-Carboxamide 4-amino-N-(phenylmethyl)-4-piperidinecarboxamide 4-Piperidinecarboxamide, 4-amino-1-(phenylmethyl)- 4-PiperidinecarboxaMide, 4-aMino-1-(phenylMethyl)-
CAS	170921-49-0
InChI	InChI=1/C13H19N3O/c14-12(17)13(15)6-8-16(9-7-13)10-11-4-2-1-3-5-11/h1-5H,6-10,15H2,(H2,14,17)

N-Benzyl-4-Amino-Piperidine-4-Carboxamide - Physico-chemical Properties

Molecular Formula	C13H19N3O
Molar Mass	233.31
Density	1.165±0.06 g/cm3(Predicted)
Boling Point	417.0±45.0 °C(Predicted)
Flash Point	205.976°C
Vapor Presure	0mmHg at 25°C
pKa	15.84±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
Refractive Index	1.588

N-Benzyl-4-Amino-Piperidine-4-Carboxamide - Introduction

N-Benzyl-4-Amino-Piperidine-4-Carboxamide, also known as BAPNA, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C15H17N3O
-Molecular weight: 255.32g/mol
-Solubility: Soluble in organic solvents (such as ethanol, dimethylformamide, etc.)
-Melting Point: about 134-136 ℃

Use:
- BAPNA is a commonly used enzyme substrate, mainly used in methods for determining protease activity. It can react with the enzyme to generate a yellow product, and the activity of the enzyme is determined according to the absorbance change of the yellow product.
-It is often used to determine the activity of amino acid enzymes such as trypsin, amino acid enzymes and polypeptidases.

Method:
- BAPNA is generally prepared by chemical synthesis. First, benzylamine is converted to 4-aminopiperidine by a series of reactions. Then, 4-aminopiperidine was reacted with methyl formate to give N-Benzyl-4-Amino-Piperidine-4-Carboxamide.

Safety Information:
- BAPNA is a chemical reagent, and its use should follow laboratory safety procedures and personal protective measures.
-It is an irritant substance and may cause irritation to the skin, eyes and respiratory system. Avoid direct contact with skin and eyes during use, and maintain good ventilation conditions.
-If accidentally exposed or inhaled BAPNA, immediately rinse the affected area with plenty of water and seek medical help.
- BAPNA should be stored in a dry, cool place, away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15