N-Benzyloxycarbonyl-O-benzyl-L-threonine - Names and Identifiers
Name | Z-Thr(Bzl)-OH . DCHA
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Synonyms | Z-THR(BZL) z-Thr(bzl) Z-Thr(Bzl)-OH Z-L-Thr(Bzl)-OH Z-THR(BZL)-OH DCHA Z-Thr(Bzl)-OH . DCHA N-a-(O-Bzl)-CBZ-L-Thr N-Z-O-Benzyl-L-threonine Cbz-O-benzyl-L-threonine N-ALPHA-CBZ-O-BENZYL-L-THREONINE O-Benzyl-N-benzyloxycarbonyl-L-threonine N-Benzyloxycarbonyl-O-benzyl-L-threonine O-benzyl-N-[(benzyloxy)carbonyl]-L-threonine N-alpha-Benzyloxycarbonyl-O-benzyl-L-threonine N-ALPHA-CARBOBENZOXY-D-THREONINE BENZYL ETHER DICYCLOHEXYLAMMONIUM SALT
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CAS | 69863-36-1 201275-72-1
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InChI | InChI=1/C19H21NO5/c1-14(24-12-15-8-4-2-5-9-15)17(18(21)22)20-19(23)25-13-16-10-6-3-7-11-16/h2-11,14,17H,12-13H2,1H3,(H,20,23)(H,21,22)/t14-,17+/m1/s1 |
N-Benzyloxycarbonyl-O-benzyl-L-threonine - Physico-chemical Properties
Molecular Formula | C19H21NO5
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Molar Mass | 343.37 |
Density | 1.228±0.06 g/cm3(Predicted) |
Melting Point | 77-80°C(lit.) |
Boling Point | 539.3±50.0 °C(Predicted) |
Flash Point | 280°C |
Vapor Presure | 1.84E-12mmHg at 25°C |
Appearance | Solid |
pKa | 3.48±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.572 |
N-Benzyloxycarbonyl-O-benzyl-L-threonine - Risk and Safety
N-Benzyloxycarbonyl-O-benzyl-L-threonine - Introduction
Z-Thr(Bzl)-OH . DCHA(Z-Thr(Bzl)-OH . DCHA) is an organic compound, its molecular formula is C25H25NO5, has certain characteristics and uses.
Nature:
Z-Thr(Bzl)-OH . DCHA is a solid powder that can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) or acetonitrile. It is stable at normal temperatures, but may decompose at high temperatures.
Use:
Z-Thr(Bzl)-OH . DCHA is widely used in organic synthesis. It is often used as an intermediate in the synthesis of other compounds, for example for the synthesis of peptides or hormones. Because it has a protecting group, it can prevent the amino group in the benzoyl amino acid from participating in the reaction, thereby ensuring a specific synthesis path of the target compound.
Preparation Method:
The preparation of Z-Thr(Bzl)-OH . DCHA can usually be obtained by reacting threonine with benzoyl chloride and diphenyl methyl carbonate. During the reaction, benzoyl chloride was used as a protecting group introducing agent, and dibenzyl carbonate was used to provide the benzoyloxy group. The final product can be purified by crystallization or column chromatography to obtain Z-Thr(Bzl)-OH . DCHA with high purity.
Safety Information:
The safety of Z-Thr(Bzl)-OH . DCHA has not been studied and evaluated in detail, so pay attention to safe operation and use it in a laboratory environment. During use, direct contact with skin and eyes should be avoided, and appropriate personal protective equipment such as laboratory gloves and goggles should be worn when necessary. In addition, the inhalation of dust or gas should be avoided. In the event of an accident, seek immediate medical assistance.
Last Update:2024-04-10 22:29:15