N-Boc-(S)-2-amino-3-benzyloxy-1-propanol
N-Boc-(S)-2-amino-3-benzyloxy-1-propanol
CAS: 79069-15-1
Molecular Formula: C15H23NO4
N-Boc-(S)-2-amino-3-benzyloxy-1-propanol - Names and Identifiers
N-Boc-(S)-2-amino-3-benzyloxy-1-propanol - Physico-chemical Properties
| Molecular Formula | C15H23NO4 |
| Molar Mass | 281.35 |
| Density | 1.105 |
| Melting Point | 66-69°C(lit.) |
| Boling Point | 443.1±40.0 °C(Predicted) |
| Specific Rotation(α) | -14 º (c=1 in chloroform) |
| pKa | 11.58±0.46(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Physical and Chemical Properties | alpha:-14 o (c=1 in chloroform) |
N-Boc-(S)-2-amino-3-benzyloxy-1-propanol - Risk and Safety
| WGK Germany | 3 |
N-Boc-(S)-2-amino-3-benzyloxy-1-propanol - Introduction
N-Boc-(S)-is an organic compound with the following properties:
1. Appearance: white or almost white crystal powder.
2. molecular formula and molecular weight: C14H23NO3, molecular weight is 257.34.
3. Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
4. Thermal stability: It has certain thermal stability and can be heated under appropriate conditions.
5. optical properties: with optical activity, is a kind of optical compounds.
The main use of N-Boc-(S)-is as a chiral reagent in organic synthesis for the synthesis of chiral compounds. Because of its chiral structure, it can be used as a chiral catalyst or intermediate for the synthesis of chiral drugs, pesticides and natural products.
A common method for preparing N-Boc-(S)-will is the amidation of p-benzylanisole with (S)-alanine to give the corresponding amide compound. Then, the Boc protecting group was removed by deprotection reaction to obtain the final product.
Regarding safety information, N-Boc-(S)-is generally safe under normal use conditions, but the following precautions still need to be followed:
1. Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
2. in the operation should wear protective gloves, glasses and laboratory coat, to ensure good ventilation.
3. storage should be placed in a sealed, dark, dry place, away from fire and flammable materials.
4. in the use and handling of this compound, should follow the relevant safety procedures and the use of appropriate process conditions.
5. If the compound is accidentally ingested or inhaled, seek medical attention immediately.
1. Appearance: white or almost white crystal powder.
2. molecular formula and molecular weight: C14H23NO3, molecular weight is 257.34.
3. Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
4. Thermal stability: It has certain thermal stability and can be heated under appropriate conditions.
5. optical properties: with optical activity, is a kind of optical compounds.
The main use of N-Boc-(S)-is as a chiral reagent in organic synthesis for the synthesis of chiral compounds. Because of its chiral structure, it can be used as a chiral catalyst or intermediate for the synthesis of chiral drugs, pesticides and natural products.
A common method for preparing N-Boc-(S)-will is the amidation of p-benzylanisole with (S)-alanine to give the corresponding amide compound. Then, the Boc protecting group was removed by deprotection reaction to obtain the final product.
Regarding safety information, N-Boc-(S)-is generally safe under normal use conditions, but the following precautions still need to be followed:
1. Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
2. in the operation should wear protective gloves, glasses and laboratory coat, to ensure good ventilation.
3. storage should be placed in a sealed, dark, dry place, away from fire and flammable materials.
4. in the use and handling of this compound, should follow the relevant safety procedures and the use of appropriate process conditions.
5. If the compound is accidentally ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-09 20:02:46
