N-Boc-2-Chloroethylamine

N-Boc-2-Chloroethylamine - Names and Identifiers

Name	Carbamic acid, (2-chloroethyl)-, 1,1-dimethylethyl ester (9CI)
Synonyms	1-Boc-2-chloroethylamine N-Boc-2-Chloroethylamine tert-butyl 2-chloroethylcarbamate tert-Butyl N-(2-chloroethyl)carbamate 1-Amino-2-chloroethane, N-BOC protected 2-[(tert-Butoxycarbonyl)aMino]-1-chloroethane (2-Chloroethyl)carbamic acid 1,1-dimethylethyl ester CarbaMic acid, (2-chloroethyl)-, 1,1-diMethylethyl ester Carbamic acid, (2-chloroethyl)-, 1,1-dimethylethyl ester (9CI)
CAS	71999-74-1

N-Boc-2-Chloroethylamine - Physico-chemical Properties

Molecular Formula	C7H14ClNO2
Molar Mass	179.64
Density	1.070±0.06 g/cm3(Predicted)
Boling Point	75℃ (8 Torr)
Solubility	Chloroform (Sparingly), Methanol (Slightly)
Appearance	Colourless to Yellow Oil to Off-White to Yellow Semi-Solid
pKa	11.93±0.46(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C

N-Boc-2-Chloroethylamine - Risk and Safety

Hazard Class

IRRITANT

N-Boc-2-Chloroethylamine - Upstream Downstream Industry

Downstream Products

Methyl 1-Boc-3-pyrrolidinecarboxylate
1-N-Boc-3-Cyanopyrrolidine

N-Boc-2-Chloroethylamine - Introduction

Carbamic acid, (2-chlorophyll)-, 1,1-dimenthyyl ester (9CI) (Carbamic acid, (2-chlorophyll)-, 1,1-dimenthyyl ester (9CI)) is an organic compound, its chemical formula is C8H16ClNO2.

Nature:
Carbamic acid, (2-chlorophyll)-, 1,1-dimethylethyl ester (9CI) is a colorless liquid with a pungent odor. It is moderately volatile. The compounds are soluble in organic solvents such as ethers, alcohols and ketones at ordinary temperatures.

Use:
Carbamic acid, (2-chloroethyl)-, 1,1-dimethylethyl ester (9CI) is often used as an intermediate in organic synthesis. It can generate 2-chloroethylamine through the reaction of deprotecting group, which is then further used in the synthesis of various organic compounds.

Method:
Carbamic acid, (2-chloroethyl)-, 1,1-dimethylethyl ester (9CI) is usually prepared by esterification of chloroethylamine with chlorinated tert-butyl carboxylate. The specific steps are: reacting tert-butyl carboxylate chloride and chloroethylamine in an organic solvent under appropriate conditions, and then obtaining the target product through an appropriate purification process.

Safety Information:
Carbamic acid, (2-chlorophyll)-, 1,1-dimethylethyl ester (9CI) Avoid skin contact, inhalation or ingestion during operation. Operate in a well-ventilated area and wear protective gloves and goggles. In case of accidental contact, rinse immediately with plenty of water and seek medical help. During storage, it should be kept in a sealed container, away from heat and fire sources.

Last Update：2024-04-10 22:29:15