N-Bocaminooxy-aceticacid2,5-dioxo-pyrrolidin-1-ylester - Names and Identifiers
N-Bocaminooxy-aceticacid2,5-dioxo-pyrrolidin-1-ylester - Physico-chemical Properties
Molecular Formula | C11H16N2O7
|
Molar Mass | 288.25 |
Melting Point | 108-110°C |
Storage Condition | Room Temprature |
N-Bocaminooxy-aceticacid2,5-dioxo-pyrrolidin-1-ylester - Introduction
(t-Boc-aminooxyacetic Acid N-Hydroxysuccinimide Ester) is a compound whose properties, uses, preparation methods and safety information are as follows:
Nature:
-Molecular formula: C13H19N3O6
-Molecular weight: 313.31g/mol
-Appearance: Colorless to yellow powder
-melting point: about 130-140 ℃
Use:
-It is widely used as a coupling reagent in biochemistry and medicinal chemistry.
-In solid phase synthesis, it can be used to synthesize peptides or proteins, linking amino acids with other compounds.
-It can also be used to prepare small molecule drugs with active groups.
Preparation Method:
-The preparation of the t-Boc-aminooxyacetic Acid N-Hydroxysuccinimide Ester generally involves the following steps:
1. First, a tert-butoxycarbonyl protecting agent (t-Boc) is added to aminooxyacetic acid to react to generate a t-Boc-aminooxyacetic acid.
2. Then, N-hydroxysuccinimide was added to the reaction system to generate the target product t-Boc-aminooxyacetic Acid N-Hydroxysuccinimide Ester.
Safety Information:
-It may be irritating to the eyes, respiratory system and skin, so it is necessary to take appropriate safety measures when handling, such as wearing protective gloves, goggles and protective masks.
-It should be used in a well-ventilated place and avoid inhalation or ingestion of compounds.
-After treatment, the workbench and equipment should be thoroughly cleaned to avoid mixing with other chemicals.
Last Update:2024-04-09 21:01:54