N-CARBOBENZOXY-D-THREONINE
Z-D-threonine
CAS: 80384-27-6
Molecular Formula: C12H15NO5
N-CARBOBENZOXY-D-THREONINE - Names and Identifiers
| Name | Z-D-threonine |
| Synonyms | Z-D-Thr-OH Z-D-THR-OH Z-D-threonine Cbz-D-threonine N-Cbz-D-threonine N-CBZ-D-THREONINE Z-D-THREONINE extrapure N-CARBOBENZOXY-D-THREONINE N-Cbz-D-threonine Z-D-Thr-OH N-Benzyloxycarbonyl-D-threonine~Z-D-Thr-OH (2R)-2-benzyloxycarbonylamino-3-hydroxy-butanoic acid (2R,3S)-2-(benzyloxycarbonylamino)-3-hydroxybutanoic acid |
| CAS | 80384-27-6 |
| InChI | InChI=1/C12H15NO5/c1-8(14)10(11(15)16)13-12(17)18-7-9-5-3-2-4-6-9/h2-6,8,10,14H,7H2,1H3,(H,13,17)(H,15,16)/t8?,10-/m1/s1 |
N-CARBOBENZOXY-D-THREONINE - Physico-chemical Properties
| Molecular Formula | C12H15NO5 |
| Molar Mass | 253.25 |
| Density | 1.309±0.06 g/cm3(Predicted) |
| Melting Point | 100-102°C |
| Boling Point | 483.7±45.0 °C(Predicted) |
| Flash Point | 246.3°C |
| Vapor Presure | 3.62E-10mmHg at 25°C |
| BRN | 4695777 |
| pKa | 3.58±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 5 ° (C=2, AcOH) |
| MDL | MFCD00037808 |
N-CARBOBENZOXY-D-THREONINE - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29241990 |
N-CARBOBENZOXY-D-THREONINE - Introduction
Z-D-threonine(Z-D-threonine) is an amino acid derivative whose chemical structure contains the side chain of threonine, and the side chain is protected as a benzyloxycarbonyl group.
Nature of Z-D-threonine:
Z-D-threonine is a white crystalline solid, soluble in water and acidic solutions. It is an optically active molecule, and there are two isomers, D mirror and L mirror.
Purpose of Z-D-threonine:
Z-D-threonine are often used in organic synthesis as chiral reagents, especially in the synthesis of polypeptides. It can be used as a protecting group for L-threonine to control chirality during polypeptide synthesis.
Preparation of Z-D-threonine:
Preparation of Z-D-threonine The hydroxyl group of threonine is usually protected as a benzyloxycarbonyl group by reaction with D-threonine. The specific synthesis method can be selected according to different literature and synthesis requirements.
Z-D-threonine safety information:
Although there are few specific toxicity data on Z-D-threonine, amino acid derivatives generally have low toxicity in general. However, when used as a laboratory reagent, it is still necessary to follow chemical safety practices and take appropriate personal protective measures, such as wearing gloves, goggles and lab clothes. During use and handling, please avoid contact with skin and eyes, and ensure that you operate under well-ventilated conditions. If unexpected exposure or discomfort occurs, medical help should be sought immediately.
Nature of Z-D-threonine:
Z-D-threonine is a white crystalline solid, soluble in water and acidic solutions. It is an optically active molecule, and there are two isomers, D mirror and L mirror.
Purpose of Z-D-threonine:
Z-D-threonine are often used in organic synthesis as chiral reagents, especially in the synthesis of polypeptides. It can be used as a protecting group for L-threonine to control chirality during polypeptide synthesis.
Preparation of Z-D-threonine:
Preparation of Z-D-threonine The hydroxyl group of threonine is usually protected as a benzyloxycarbonyl group by reaction with D-threonine. The specific synthesis method can be selected according to different literature and synthesis requirements.
Z-D-threonine safety information:
Although there are few specific toxicity data on Z-D-threonine, amino acid derivatives generally have low toxicity in general. However, when used as a laboratory reagent, it is still necessary to follow chemical safety practices and take appropriate personal protective measures, such as wearing gloves, goggles and lab clothes. During use and handling, please avoid contact with skin and eyes, and ensure that you operate under well-ventilated conditions. If unexpected exposure or discomfort occurs, medical help should be sought immediately.
Last Update：2024-04-09 20:45:29
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