N-Cbz-3-pyrrolidinol

N-Cbz-3-pyrrolidinol - Names and Identifiers

Name	3-hydroxy-1-N-CBZ-pyrrolidine
Synonyms	N-CBZ-3 3-HYDROXY-1-N-CBZ-PY N-Cbz-3-pyrrolidinol N-CBZ-3-HYDROXYPYRROLIDINE N-CBZ-3-hydroxypyrrolidine 1-Cbz-3-hydroxy-pyrrolidine 3-HYDROXY-1-N-CBZ-PYRROLIDINE 3-hydroxy-1-N-CBZ-pyrrolidine BENZYL 3-HYDROXYPYRROLIDINE-1-CARBOXYLATE Benzyl 3-hydroxypyrrolidine-1-Carboxylate 3-HYDROXY-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER 3-HYDROXY-pyrrolidine-1-Carboxylic acid Benzyl ester 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, phenylMethyl ester
CAS	95656-88-5
InChI	InChI=1/C12H15NO3/c14-11-6-7-13(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2

N-Cbz-3-pyrrolidinol - Physico-chemical Properties

Molecular Formula	C12H15NO3
Molar Mass	221.25
Density	1.263±0.06 g/cm3(Predicted)
Boling Point	370.7±42.0 °C(Predicted)
Flash Point	178°C
Vapor Presure	3.75E-06mmHg at 25°C
pKa	14.72±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.589

N-Cbz-3-pyrrolidinol - Introduction

It is an organic compound whose chemical structure is HOC5H9NHCOCH2C6H4CO2.

Nature:
It is a white crystal or crystalline powder with a high melting point and boiling point. It is insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide. It is stable in the air and does not easily decompose under light.

Use:
It is a commonly used organic synthesis intermediate that can be used to synthesize a variety of active compounds. It has a wide range of applications in the field of medicine, pesticides and materials science. For example, it can be used in the synthesis of opioid precursor compounds, synthetic pesticides and synthetic polymers.

Preparation Method:
The preparation method of Lin is usually to react 3-aminopyrroline with N-CBZ acid chloride or N-CBZ anhydride to generate Lin. In the reaction process requires the participation of organic solvents and catalysts. The specific conditions of the preparation method will be adjusted according to the actual situation.

Safety Information:
It is less toxic and dangerous, but it is still necessary to follow general laboratory safety practices. Avoid inhalation, ingestion or contact with skin during operation. Wear appropriate protective gloves, glasses and protective clothing when using. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 19:05:53