N-GAMMA-TRITYL-L-GLUTAMINE
H-Gln(Trt)-OH
CAS: 102747-84-2
Molecular Formula: C24H24N2O3
N-GAMMA-TRITYL-L-GLUTAMINE - Names and Identifiers
| Name | H-Gln(Trt)-OH |
| Synonyms | H-GLN(TRT)-OH H-Glu(Trt)-OH H-Gln(Trt)-OH H-L-Gln(Trt)-OH GLUTAMINE(TRT)-OH H-Gln(Trt)-OH·H2O L-GLUTAMINE (TRITYL) N-δ-Trityl-L-glutamine N-D-Trityl-L-glutamine N-GAMMA-TRITYL-L-GLUTAMINE N-DELTA-TRITYL-L-GLUTAMINE (2S)-2-ammonio-5-oxo-5-(tritylamino)pentanoate |
| CAS | 102747-84-2 |
| InChI | InChI=1/C24H24N2O3/c25-21(23(28)29)16-17-22(27)26-24(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17,25H2,(H,26,27)(H,28,29)/t21-/m0/s1 |
N-GAMMA-TRITYL-L-GLUTAMINE - Physico-chemical Properties
| Molecular Formula | C24H24N2O3 |
| Molar Mass | 388.46 |
| Density | 1.214±0.06 g/cm3(Predicted) |
| Boling Point | 658.0±55.0 °C(Predicted) |
| Flash Point | 351.7°C |
| Vapor Presure | 3.28E-18mmHg at 25°C |
| pKa | 2.22±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.613 |
N-GAMMA-TRITYL-L-GLUTAMINE - Introduction
N'-Trityl-L-glutamine is an organic compound, also known as Boc-L-Gln-OH. It has the following properties:
1. Appearance: White crystalline solid.
2. solubility: soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
3. melting point: about 79-81 degrees Celsius.
4. molecular formula: C20H21N3O4.
5. molecular weight: 363.40.
N'-trityl-L-glutamine is mainly used as a protecting group in organic synthesis, which can be removed by hydrolysis under acid or alkali conditions. It has important applications in peptide synthesis, drug manufacture and synthesis of biologically active polypeptides.
N'-Trityl-L-glutamine can be prepared:
1. trityl amine is reacted with L-glutamyl chloride to obtain N'-trityl-L-glutamine.
2. Boc-glutamic acid was reacted with trityl under alkaline conditions.
Regarding safety information, you need to pay attention to the following:
1. should avoid contact with skin, eyes and respiratory tract, wear protective equipment.
2. avoid inhalation of dust or solution vapor.
3. should be stored away from the fire and oxidant.
4. When handling or using, pay attention to comply with the safety operation procedures of the chemical laboratory.
1. Appearance: White crystalline solid.
2. solubility: soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
3. melting point: about 79-81 degrees Celsius.
4. molecular formula: C20H21N3O4.
5. molecular weight: 363.40.
N'-trityl-L-glutamine is mainly used as a protecting group in organic synthesis, which can be removed by hydrolysis under acid or alkali conditions. It has important applications in peptide synthesis, drug manufacture and synthesis of biologically active polypeptides.
N'-Trityl-L-glutamine can be prepared:
1. trityl amine is reacted with L-glutamyl chloride to obtain N'-trityl-L-glutamine.
2. Boc-glutamic acid was reacted with trityl under alkaline conditions.
Regarding safety information, you need to pay attention to the following:
1. should avoid contact with skin, eyes and respiratory tract, wear protective equipment.
2. avoid inhalation of dust or solution vapor.
3. should be stored away from the fire and oxidant.
4. When handling or using, pay attention to comply with the safety operation procedures of the chemical laboratory.
Last Update：2024-04-09 21:21:28
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CAS: 102747-84-2
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