N-Methyl-p-aminoacetophenone

N-Methyl-p-aminoacetophenone - Names and Identifiers

Name	1-(4-(methylamino)phenyl)ethanone
Synonyms	p-Acetyl-N-methylaniline 4-Acetyl-N-methylaniline N-Methyl-4-acetylaniline p-Methylaminoacetophenone 4-N-Methylaminoacetophenone 4'-(Methylamino)acetophenone N-Methyl-p-aminoacetophenone 1-(4-(methylamino)phenyl)ethanone Ethanone, 1-[4-(methylamino)phenyl]- (9CI)
CAS	17687-47-7

N-Methyl-p-aminoacetophenone - Physico-chemical Properties

Molecular Formula	C9H11NO
Molar Mass	149.19
Density	1.062±0.06 g/cm3(Predicted)
Melting Point	103-107 °C
Boling Point	281.7±23.0 °C(Predicted)
Appearance	Shape Solid, color White to pale brown
pKa	1.96±0.12(Predicted)
Storage Condition	Inert atmosphere,Room Temperature

N-Methyl-p-aminoacetophenone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.
WGK Germany	2

N-Methyl-p-aminoacetophenone - Upstream Downstream Industry

Raw Materials	Ethanone,1-[4-[(methylsulfonyl)oxy]phenyl]- 4'-DIMETHYLAMINOACETOPHENONE 4'-Iodoacetophenone 4-Aminoacetophenone Methanol Methylamine 4'-Bromoacetophenone Iodomethane Methylboronic acid
Downstream Products	Carbamic acid, N-(4-acetylphenyl)-, methyl ester NISTC4150372 2-[(4-NITROPHENYL)SULFANYL]ACETIC ACID

N-Methyl-p-aminoacetophenone - Introduction

1-(4-(methylamino)phenyl)ethanone is an organic compound with molecular structure C10H13NO.

Nature:
1-(4-(methylamino)phenyl)ethanone is a solid, light yellow crystalline in appearance. It is soluble in organic solvents such as ethanol and dimethylformamide at room temperature. It has a moderate melting point and boiling point, and is weak in light and thermal stability.

Use:
1-(4-(methylamino)phenyl)ethanone is commonly used in organic synthesis and medicine. It can be used as a raw material for the synthesis of other compounds, such as synthetic intermediates for drug molecules. In addition, it can also be used as dye synthesis, fluorescent probe and chemical sensor preparation.

Method:
1-(4-(methylamino)phenyl)ethanone can be synthesized by acetylation of aniline. Typically, aniline is reacted with acetic anhydride under basic conditions to give 1-(4-(methylamino)phenyl)ethanone. The reaction is usually carried out at low temperature, and the yield and purity are controlled by appropriate process conditions.

Safety Information:
1-(4-(methylamino)phenyl)ethanone is a chemical substance, which needs to be safe when used. It is an irritant and dangerous substance and may cause irritation to the skin, eyes and respiratory tract. Appropriate protective measures should be taken during operation, including wearing goggles, gloves and respiratory protection equipment. During storage and handling, care should be taken to avoid contact with oxidants and ignition sources to prevent the risk of fire and explosion.

Last Update：2024-04-09 20:52:54