N-PHTALOYL-L-PHENYLALANINE

N-PHTALOYL-L-PHENYLALANINE - Names and Identifiers

Name	N-phthaloyl-L-phenylalanine
Synonyms	PHT-PHE-OH N-Phthaloyl-Phe-OH PHTHALYL-L-PHENYLALANINE N-Phthaloyl-Phenylalanine PHTHALOYL-L-PHENYLALANINE N-PHTALOYL-L-PHENYLALANINE N-phthaloyl-L-phenylalanine N-PHTHALOYL-L-PHENYLALANINE N-PHTHALOYL-L-PHENYLALANINE extrapure (2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid (2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid
CAS	5123-55-7
InChI	InChI=1/C17H13NO4/c19-15-12-8-4-5-9-13(12)16(20)18(15)14(17(21)22)10-11-6-2-1-3-7-11/h1-9,14H,10H2,(H,21,22)/t14-/m0/s1

N-PHTALOYL-L-PHENYLALANINE - Physico-chemical Properties

Molecular Formula	C17H13NO4
Molar Mass	295.29
Density	1.358 g/cm3
Melting Point	181-185°C
Boling Point	498.0±38.0 °C(Predicted)
Flash Point	255°C
Solubility	Soluble in methanol. (almost transparency)
Vapor Presure	9.78E-11mmHg at 25°C
Appearance	Powder
Color	White
pKa	3.50±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Hygroscopic
Refractive Index	-216.5 ° (C=2, EtOH)
MDL	MFCD00069738

N-PHTALOYL-L-PHENYLALANINE - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	3-10
HS Code	29242990

N-PHTALOYL-L-PHENYLALANINE - Introduction

N-phthaloyl-L-phenylalanine is an organic compound whose chemical formula is C18H15NO4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: N-phthaloyl-L-phenylalanine is a white crystalline solid.
-Solubility: It is almost insoluble in water, but can be dissolved in organic solvents, such as ethanol, methanol and chloroform.
-Melting point: The melting point of the N-phthaloyl-L-phenylalanine is about 142-144°C.
-Hydrolytic stability: It is relatively stable under acidic conditions.

Use:
N-phthaloyl-L-phenylalanine have many applications in chemistry and biochemistry:
-As an active site protector: It can be used as a substrate protector in enzyme-catalyzed reactions to protect the active site of the substrate.
-As an inducer: It can be used to synthesize chiral compounds, such as chiral drugs and synthetic materials.
-As an intermediate in organic synthesis: It can be used to synthesize compounds with specific structures and functions, such as polymers and materials.

Preparation Method:
The preparation of N-phthaloyl-L-phenylalanine is generally carried out by the following steps:
1. Using phthalic acid and L-phenylalanine as raw materials, ester exchange reaction was carried out under appropriate conditions to prepare N-phthaloyl-L-phenylalanine ester.
2. hydrolyze the N-phthaloyl-L-phenylalanine ester to obtain the N-phthaloyl-L-phenylalanine.

Safety Information:
- N-phthaloyl-L-phenylalanine security data is still limited and needs to be handled carefully.
-Care should be taken to wear appropriate protective equipment, such as laboratory gloves, masks, and goggles, when using or handling the compound.
-Avoid inhaling dust of the substance, contact with the skin, or getting into the eyes.
-When using the compound, it should be placed in a well-ventilated environment and avoid contact with strong acids and strong bases.

Please note that the properties, uses and safety information of this compound are for reference only, and specific use should be subject to relevant laboratory or professional guidance.

Last Update：2024-04-09 15:17:58