N-Phenyl-2-chloro-2-(2-phenylhydrazono)acetamide
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride
CAS: 33101-93-8
Molecular Formula: C14H12ClN3O
N-Phenyl-2-chloro-2-(2-phenylhydrazono)acetamide - Names and Identifiers
N-Phenyl-2-chloro-2-(2-phenylhydrazono)acetamide - Physico-chemical Properties
| Molecular Formula | C14H12ClN3O |
| Molar Mass | 273.72 |
| Density | 1.23 |
| Melting Point | 159 °C |
| Refractive Index | 1.607 |
N-Phenyl-2-chloro-2-(2-phenylhydrazono)acetamide - Introduction
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride, also known as (1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless to pale yellow crystalline solid.
-Solubility: It has good solubility in common solvents (such as ethanol, methanol and dichloromethane).
Use:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is a common organic synthesis intermediate. It can be used to synthesize various nitrogen-containing heterocyclic compounds, such as pyrazoline compounds, oxazoline compounds, etc. These compounds have a wide range of applications in the field of pharmaceuticals and pesticides.
Method:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is typically prepared by reacting N-phenyl-2-(anilino) acetamide with thionyl chloride. The reaction is typically carried out under an inert atmosphere, catalyzed by the addition of a nucleophile such as ferric chloride, and at an appropriate temperature.
Safety Information:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is a chemical and should be handled with caution. Wear protective gloves and eye protection during handling or operation to avoid skin and eye contact. Avoid inhaling its dust or vapors and ensure that it is operated in a well-ventilated place. In case of inadvertent contact, immediately flush the affected area with plenty of water and seek medical assistance. In addition, it should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable substances.
Nature:
-Appearance: It is a colorless to pale yellow crystalline solid.
-Solubility: It has good solubility in common solvents (such as ethanol, methanol and dichloromethane).
Use:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is a common organic synthesis intermediate. It can be used to synthesize various nitrogen-containing heterocyclic compounds, such as pyrazoline compounds, oxazoline compounds, etc. These compounds have a wide range of applications in the field of pharmaceuticals and pesticides.
Method:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is typically prepared by reacting N-phenyl-2-(anilino) acetamide with thionyl chloride. The reaction is typically carried out under an inert atmosphere, catalyzed by the addition of a nucleophile such as ferric chloride, and at an appropriate temperature.
Safety Information:
(1Z)-2-oxo-N-phenyl-2-(phenylamino)ethanehydrazonoyl chloride is a chemical and should be handled with caution. Wear protective gloves and eye protection during handling or operation to avoid skin and eye contact. Avoid inhaling its dust or vapors and ensure that it is operated in a well-ventilated place. In case of inadvertent contact, immediately flush the affected area with plenty of water and seek medical assistance. In addition, it should be stored in a dry, cool, well-ventilated place, away from fire sources and flammable substances.
Last Update：2024-04-09 20:52:54
