N-Tosylacetamide

N-Tosylacetamide - Names and Identifiers

Name	N-(4-Methylphenyl)sulfonylacetamide
Synonyms	N-Tosylacetamide N-P-TOSYL-ACETAMIDE N-p-Tosyl-Acetamide N-ACETYL-4-TOLUENE SULFONAMIDE N-ACETYL-P-TOLUENE SULFONAMIDE N-ACETYL-O,P-TOLUENESULFONAMIDE N-(4-METHYLPHENYL)SULFONYLACETAMIDE N-(4-Methylphenyl)sulfonylacetamide N-(4-methylphenyl)sulfonylethanamide N-[(4-Methylphenyl)sulfonyl]acetamide Acetamide, N-[(4-methylphenyl)sulfonyl]- acetamide, N-[(4-methylphenyl)sulfonyl]-
CAS	1888-33-1
InChI	InChI=1/C9H11NO3S/c1-7-3-5-9(6-4-7)14(12,13)10-8(2)11/h3-6H,1-2H3,(H,10,11)

N-Tosylacetamide - Physico-chemical Properties

Molecular Formula	C9H11NO3S
Molar Mass	213.25
Density	1.254g/cm³
Melting Point	140 °C
Appearance	powder to crystal
Color	White to Almost white
Storage Condition	2-8℃
Refractive Index	1.538

N-Tosylacetamide - Introduction

N-(4-Methylphenyl)sulfonylacetamide(N-acetylp-toluenesulfonamide) is an organic compound with the chemical formula C9H11NO3S.

Nature:
N-(4-Methylphenyl)sulfonylacetamide is a white crystalline powder, almost insoluble in water at room temperature, but soluble in organic solvents such as ethanol, acetone, etc. It is an amide compound capable of forming hydrogen bonds and other intermolecular interactions.

Use:
N-(4-Methylphenyl)sulfonylacetamide is widely used in medicine, cosmetics, dyes and other fields. It can be used as a drug intermediate for the synthesis of antibacterial, antiviral and other active compounds. In addition, it can also be used as a plasticizer, cosmetic preservative, Dye auxiliary, etc.

Method:
There are many methods for preparing N-(4-Methylphenyl)sulfonylacetamide. The commonly used methods include the reaction of p-toluenesulfonamide with acetic anhydride under alkaline conditions to generate N-(4-Methylphenyl)sulfonylacetamide. During the reaction, it is necessary to control the reaction temperature and reaction time to improve the yield and purity.

Safety Information:
N-(4-Methylphenyl)sulfonylacetamide is generally considered to be relatively safe under normal use conditions, but the following matters still need to be paid attention:
1. Avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water and seek medical attention.
2. Avoid inhaling its dust, can take protective measures such as wearing a mask.
3. Storage should be placed in a dry and ventilated place, away from fire sources and strong oxidants.
4. In the process of use, it is strictly prohibited to contact with flammable substances, acids and other substances.

Although the safety assessment of N-(4-Methylphenyl)sulfonylacetamide has been carried out, the specific safe operation and storage should follow the correct chemical laboratory operating procedures and relevant safety measures.

Last Update：2024-04-09 19:05:47