N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine - Names and Identifiers
N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine - Physico-chemical Properties
Molecular Formula | C25H28N2O6
|
Molar Mass | 452.5 |
Density | 1.237±0.06 g/cm3(Predicted) |
Boling Point | 689.7±55.0 °C(Predicted) |
pKa | 3.96±0.21(Predicted) |
Storage Condition | 2-8°C |
N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine - Introduction
Alloc-L-Lys(Fmoc)-OH (Alloc-L-Lys(Fmoc)-OH) is an organic compound commonly used in the synthesis of polypeptides and proteins. The following is a detailed description of the properties, uses, preparation methods and safety information of the compound.
Nature:
-Molecular formula: C44H45N3O7
-Molecular weight: 733.85g/mol
-Appearance: White crystal or powder
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), methanol and ethanol, insoluble in water
Use:
- Alloc-L-Lys(Fmoc)-OH is a reagent that protects amino acids and plays an important role in the synthesis of peptides and proteins.
-It can be used to synthesize various protected amino acid substitutes, as well as to construct the starting material of the peptide chain and the extension of the subsequent chain.
Preparation Method:
The synthesis of-Alloc-L-Lys(Fmoc)-OH is generally accomplished in a two-step reaction. First, fluorenemol and diethyl carbonate are reacted to obtain N6-[fluorenylmethoxycarbonyl]-L-lysine, and then 2-propenyl alcohol and carbon dioxide are reacted to obtain the final product Alloc-L-Lys(Fmoc)-OH.
Safety Information:
- Alloc-L-Lys(Fmoc)-OH is an organic synthesis reagent that needs to be used and stored in a laboratory environment.
-This compound may be irritating to the eyes, skin and respiratory system. Wear protective gloves, glasses and a mask to ensure adequate ventilation.
-Alloc-L-Lys(Fmoc)-OH should be kept away from fire and high temperature, stored in a dry and cool place, and isolated from harmful substances such as organic solvents and oxidants.
-The specific hazards and safety measures of this compound need to be understood in detail and safe laboratory operations before use.
Last Update:2024-04-10 22:29:15