N-benzyloxycarbonyl-DL-tryptophan - Names and Identifiers
Name | N-CBZ-DL-Tryptophan
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Synonyms | Z-DL-TRP Z-DL-TRP-OH Z-DL-Trp-OH Z-DL-TRYPTOPHAN Cbz-DL-tryptophan AKOS BBS-00007675 N-CBZ-DL-Tryptophan N-CBZ-DL-TRYPTOPHAN Carbobenzoxytryptophan N-Carbobenzoxy-DL-tryptophan N-CARBOBENZOXY-DL-TRYPTOPHAN N-Carbobenzyloxy-DL-tryptophan N-benzyloxycarbonyl-DL-tryptophan N-[(benzyloxy)carbonyl]tryptophan N-BENZYLOXYCARBONYL-DL-TRYPTOPHAN N-ALPHA-CARBOBENZOXY-DL-TRYPTOPHAN
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CAS | 13058-16-7
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EINECS | 235-949-1 |
InChI | InChI=1/C19H18N2O4/c22-18(23)17(10-14-11-20-16-9-5-4-8-15(14)16)21-19(24)25-12-13-6-2-1-3-7-13/h1-9,11,17,20H,10,12H2,(H,21,24)(H,22,23) |
N-benzyloxycarbonyl-DL-tryptophan - Physico-chemical Properties
Molecular Formula | C19H18N2O4
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Molar Mass | 338.36 |
Density | 1.341±0.06 g/cm3(Predicted) |
Melting Point | 170 °C |
Boling Point | 619.1±55.0 °C(Predicted) |
Flash Point | 328.2°C |
Solubility | almost transparency in Methanol |
Vapor Presure | 3.46E-16mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Yellow to Orange |
pKa | 3.98±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.662 |
MDL | MFCD00069707 |
N-benzyloxycarbonyl-DL-tryptophan - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
HS Code | 29339900 |
N-benzyloxycarbonyl-DL-tryptophan - Introduction
Cbz-DL-tryptophan, fully known as N-protector-DL-tryptophan (Carbobenzyloxy-DL-phenylalanine), is an organic compound. The following is a description of the properties, uses, preparation and safety information of Cbz-DL-tryptophan:
Nature:
- Cbz-DL-Tryptophan is a white crystalline powder with a special smell.
-It is relatively stable at room temperature, but may degrade under high temperature, acidic or alkaline conditions.
-Its chemical structure contains a protective group (Cbz group), which is mainly used to protect the amino group in DL-tryptophan.
Use:
- Cbz-DL-tryptophan is mainly used as an intermediate in organic synthesis and is used to synthesize other compounds.
-it is commonly used in the synthesis of peptide drugs, peptide antibiotics and so on.
Preparation Method:
-The preparation of Cbz-DL-tryptophan is usually carried out by the following steps:
1. DL-tryptophan reacts with chloromethyl phenyl ketone to generate N-protecting group-DL-tryptophan.
2. Cbz-DL-tryptophan with high purity was obtained by crystallization or column chromatography.
Safety Information:
- Cbz-DL-Tryptophan is a chemical, and you need to pay attention to safe operation when using it.
-It may be irritating to the skin, eyes and respiratory tract and should be avoided.
-During use or storage, you must maintain good ventilation, avoid inhaling dust or avoid contact with organic solvents.
-Use should wear appropriate protective equipment, such as chemical protective gloves, goggles, etc.
-Follow local codes and regulations when disposing of waste.
Last Update:2024-04-09 19:05:46