N-hydroxy-4-methoxy-1H-indole-3-carboximidamide

N-hydroxy-4-methoxy-1H-indole-3-carboximidamide - Names and Identifiers

Name	N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine
Synonyms	N-HYDROXY-4-METHOXY-1H-INDOLE-3-CARBOXAMIDINE N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine N-hydroxy-4-methoxy-1H-indole-3-carboximidamide N'-hydroxy-4-Methoxy-1H-indole-3-carboxiMidaMide 1H-Indole-3-carboxiMidaMide, N-hydroxy-4-Methoxy- 1H-indole-3-carboximidamide, N'-hydroxy-4-methoxy-
CAS	889943-82-2
EINECS	604-604-1
InChI	InChI=1/C10H11N3O2/c1-15-8-4-2-3-7-9(8)6(5-12-7)10(11)13-14/h2-5,12,14H,1H3,(H2,11,13)

N-hydroxy-4-methoxy-1H-indole-3-carboximidamide - Physico-chemical Properties

Molecular Formula	C10H11N3O2
Molar Mass	205.21
Density	1.40±0.1 g/cm3 (20 ºC 760 Torr)
Boling Point	431.1±48.0 °C(Predicted)
Flash Point	252.3°C
Vapor Presure	1.47E-10mmHg at 25°C
pKa	6.86±0.69(Predicted)
Storage Condition	2-8°C
Refractive Index	1.657

N-hydroxy-4-methoxy-1H-indole-3-carboximidamide - Introduction

N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine is an organic compound with the chemical formula C11H11N3O2. It is a kind of special structure of indole compounds, with high activity. The following is a description of the nature, use, preparation and safety information of N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine:

Nature:
-Appearance: N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine is a white to pale yellow solid.
-Melting point: about 177-183 degrees Celsius.
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane, but insoluble in water.

Use:
N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine have multiple applications in pharmaceutical and biochemical research:
-Antiviral activity: N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine are widely used in the development of anti-HIV drugs to treat infections by inhibiting viral replication.
-Anti-tumor activity: The compound has the potential to inhibit the proliferation of tumor cells and can be used in cancer treatment research.
-Other applications: N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine can also be used as an enzyme inhibitor, a dose for regulating cell proliferation, a nucleic acid fluorescent dye, etc.

Preparation Method:
N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine can be prepared in a variety of ways. A common method is to obtain the target product through a series of reactions starting from indole -3-carboxamidine.

Safety Information:
N'-hydroxy-4-methoxy-1H-indole-3-carboxamidine there is no clear report of toxicity and danger, the following safety measures should be paid attention to when using and handling:
-Avoid contact with skin and eyes, and avoid inhalation or ingestion of the compound.
-Personal protective equipment such as protective gloves, goggles and masks should be worn during operation.
-The compound should be used in a well-ventilated laboratory environment to avoid harmful gases.
-Storage should be sealed and kept away from fire and flammable substances.

Last Update：2024-04-09 02:00:48