N-methyl-5-nitropyridine-2-amine

N-methyl-5-nitropyridine-2-amine - Names and Identifiers

Name	2-Methylamino-5-nitropyridine
Synonyms	2-METHYLAMINO-5-NITROPYRIDINE 2-Methylamino-5-nitropyridine N-METHYL-5-NITRO-2-PYRIDINAMINE methyl-(5-nitro-2-pyridyl)amine N-METHYL-5-NITROPYRIDIN-2-AMINE N-methyl-5-nitropyridine-2-amine
CAS	4093-89-4
InChI	InChI=1/C6H7N3O2/c1-7-6-3-2-5(4-8-6)9(10)11/h2-4H,1H3,(H,7,8)

N-methyl-5-nitropyridine-2-amine - Physico-chemical Properties

Molecular Formula	C6H7N3O2
Molar Mass	153.14
Density	1.343g/cm³
Melting Point	178-180
Boling Point	300.8°C at 760 mmHg
Flash Point	135.7°C
Vapor Presure	0.00109mmHg at 25°C
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.629

N-methyl-5-nitropyridine-2-amine - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

N-methyl-5-nitropyridine-2-amine - Introduction

2-Methylamino-5-nitropyridine is an organic compound with the chemical formula C6H7N3O2. It is a white solid, soluble in some organic solvents, such as alcohols, ethers and ketones. The following is information about the properties, use, preparation and safety of the compound:

Nature:
-Appearance: White solid
-Molecular weight: 153.14g/mol
-Density: 1.39g/cm³
-Melting point: 93-96°C
-Boiling point: 269°C
-Low solubility in water

Use:
2-Methylamino-5-nitropyridine is an important intermediate commonly used in organic synthesis reactions. It is widely used in the fields of drug synthesis, dye synthesis, cosmetic synthesis and pesticide preparation.

Preparation Method:
The preparation of 2-Methylamino-5-nitropyridine can usually be carried out by the following steps:
1. Dissolve 2-picoline in tartrate solution.
2. adding sodium nitrite solution, the reaction generates 2-nitropyridine.
3.2-Nitropyridine is reduced to 2-Methylamino-5-nitropyridine, and sodium bisulfite can be used as a reducing agent.

Safety Information:
- 2-Methylamino-5-nitropyridine is an organic compound, you need to pay attention to its toxicity and irritation to the human body.
-Wear appropriate protective gloves, glasses and a jacket when handling the compound to avoid direct contact with skin and eyes.
-During operation, avoid inhaling the dust or vapor of the compound, and operate in a well-ventilated environment.
-If you feel unwell after accidental exposure or inhalation of the compound, you should seek medical help immediately, with detailed information about the compound.

Please note that the information provided above is for reference only. Please refer to the relevant chemical literature and operation manual for specific preparation and use, and strictly follow the laboratory safety regulations.

Last Update：2024-04-09 19:05:49