N-phenylacetyl-2-(2-chlorophenyl)-D-glycine
(2R)-(2-Chlorophenyl)[(phenylacetyl)amino]acetic acid
CAS: 1098100-07-2
Molecular Formula: C16H14ClNO3
N-phenylacetyl-2-(2-chlorophenyl)-D-glycine - Names and Identifiers
N-phenylacetyl-2-(2-chlorophenyl)-D-glycine - Physico-chemical Properties
| Molecular Formula | C16H14ClNO3 |
| Molar Mass | 303.74 |
N-phenylacetyl-2-(2-chlorophenyl)-D-glycine - Introduction
R-2-(2-Chlorophenyl)-2-(2-phenylacetamido) acetic acid is an organic compound whose chemical formula is C16H14ClNO3. The following is about R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid some properties, uses, preparation and safety information introduction:
Nature:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid is a colorless to slightly yellow crystal or a crystalline solid.
-It has low solubility at room temperature, and commonly used solvents include ethanol, dimethyl sulfoxide and dichloromethane.
-The melting point range of the compound is about 100-105 degrees Celsius.
Use:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid can be used as an important intermediate in organic synthesis and used in the synthesis of various drugs and pesticides.
-In drug development, it can be used to synthesize potential anti-cancer drugs, anti-inflammatory drugs and antibacterial drugs.
Preparation Method:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid The preparation method generally includes the reaction of p-aminoacetic acid and 2-chlorophenyl acetyl chloride.
-The reaction may be carried out under an inert atmosphere, such as a nitrogen atmosphere or an argon atmosphere.
-Usually basic media are used to catalyze the reaction, such as triethylamine, pyridine or sodium carbonate.
-After completion of the reaction, the product can be purified by crystallization or column chromatography.
Safety Information:
-When handling and storing the compound, it should be strictly in accordance with the safe operating procedures of the organic chemistry laboratory.
-Wear appropriate protective equipment, such as lab gloves, goggles and dust masks, as the compound may be harmful to the skin, eyes and respiratory system.
-Avoid direct contact and inhalation when handling this compound.
-The compound should be stored in a dry, low-temperature and well-ventilated place, away from fire and oxidizing agents.
Nature:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid is a colorless to slightly yellow crystal or a crystalline solid.
-It has low solubility at room temperature, and commonly used solvents include ethanol, dimethyl sulfoxide and dichloromethane.
-The melting point range of the compound is about 100-105 degrees Celsius.
Use:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid can be used as an important intermediate in organic synthesis and used in the synthesis of various drugs and pesticides.
-In drug development, it can be used to synthesize potential anti-cancer drugs, anti-inflammatory drugs and antibacterial drugs.
Preparation Method:
- R-2-(2-chlorophenyl)-2-(2-phenylacetamido) acetic acid The preparation method generally includes the reaction of p-aminoacetic acid and 2-chlorophenyl acetyl chloride.
-The reaction may be carried out under an inert atmosphere, such as a nitrogen atmosphere or an argon atmosphere.
-Usually basic media are used to catalyze the reaction, such as triethylamine, pyridine or sodium carbonate.
-After completion of the reaction, the product can be purified by crystallization or column chromatography.
Safety Information:
-When handling and storing the compound, it should be strictly in accordance with the safe operating procedures of the organic chemistry laboratory.
-Wear appropriate protective equipment, such as lab gloves, goggles and dust masks, as the compound may be harmful to the skin, eyes and respiratory system.
-Avoid direct contact and inhalation when handling this compound.
-The compound should be stored in a dry, low-temperature and well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:04:16
