N-tert-Butoxycarbonylnortropan-3-ol

N-tert-Butoxycarbonylnortropan-3-ol - Names and Identifiers

Name	tert-butyl 3-endo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
Synonyms	N-Boc-Nortropine N-tert-Butoxycarbonylnortropan-3-ol endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane tert-butyl 3-endo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate (3-endo)-3-Hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester endo-3-Hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid 1,1-dimethylethyl ester 8-Azabicyclo[3.2.1]octane-8-carboxylicacid, 3-hydroxy-, 1,1-dimethylethyl ester, (3-endo)-
CAS	143557-91-9

N-tert-Butoxycarbonylnortropan-3-ol - Physico-chemical Properties

Molecular Formula	C12H21NO3
Molar Mass	227.3
Density	1.146
Melting Point	141.5℃
Boling Point	328℃
Flash Point	152℃
pKa	14.79±0.20(Predicted)
Storage Condition	2-8°C

N-tert-Butoxycarbonylnortropan-3-ol - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN2811

N-tert-Butoxycarbonylnortropan-3-ol - Upstream Downstream Industry

Downstream Products

N-Boc-exo-3-aminotropane

N-tert-Butoxycarbonylnortropan-3-ol - Introduction

tert-butyl [3.2.1]octane-8-carboxylate is an organic compound. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
-chemical formula: C14H23NO3
-Molecular weight: 253.34g/mol
-Appearance: colorless liquid
-Boiling point: About 200-220 ° C
-Density: about 0.989g/cm³
-Polarity: Polarity

Use:
- tert-butyl [3.2.1]octane-8-carboxylate is often used as an intermediate in organic synthesis. It can be used to synthesize a variety of biologically active compounds, such as drugs, pesticides and antibacterial agents.

Method:
tert-butyl [3.2.1]octane-8-carboxylate can be prepared by the following steps:
1. First, tert-butyl octanoate (t-butyl hexanoate) reacts with methyl acrylate (methyl acrylate) under the catalysis of base to form tert-butyl octane-8-carboxylate (t-butyl 8-hexanoate).
2. Then, in the presence of a catalyst, tert-butyl octane-8-carboxylate was added to boron hexafluoride (boron trifluoride) and isopropylamine (isopropylamine) to form [3.2.1]octane.

Safety Information:
- tert-butyl [3.2.1]octane-8-carboxylate is a chemical and should be used and stored correctly and in accordance with relevant safety procedures.
-This compound may be irritating to the eyes, skin and respiratory system and should be used to avoid contact.
-Wear appropriate protective equipment such as safety glasses, gloves and breathing masks during use.
-In case of contact with skin or eyes, rinse immediately with water and seek medical help.

Please note that any chemicals should be used with caution and in accordance with the relevant safety procedures and recommendations for use.

Last Update：2024-04-09 21:01:54