N-tert-Butyl-2-pyrrolidone

N-tert-Butyl-2-pyrrolidone - Names and Identifiers

Name	1-(tert-butyl)pyrrolidin-2-one
Synonyms	Einecs 243-972-3 N-tert-Butyl-2-pyrrolidone 1-tert-Butyl-2-pyrrolidone 1-tert-Butyl-2-pyrrolidinone N-tert-Butyl-2-pyrrolidinone 1-(tert-butyl)pyrrolidin-2-one 1-(1,1-Dimethylethyl)pyrrolidin-2-one 2-Pyrrolidinone, 1-(1,1-dimethylethyl)-
CAS	20687-53-0
EINECS	243-972-3
InChI	InChI=1/C8H15NO/c1-8(2,3)9-6-4-5-7(9)10/h4-6H2,1-3H3

N-tert-Butyl-2-pyrrolidone - Physico-chemical Properties

Molecular Formula	C8H15NO
Molar Mass	141.21
Density	0.990
Boling Point	227℃
Flash Point	97℃
Vapor Presure	0.0804mmHg at 25°C
pKa	-0.41±0.20(Predicted)
Storage Condition	2-8℃
Refractive Index	1.477

N-tert-Butyl-2-pyrrolidone - Introduction

1-(tert-butyl)pyrrolidin-2-one is an organic compound with the chemical formula C10H15NO. The following is an introduction to its nature, use, preparation and safety information:

1. Nature:
-Appearance: 1-(tert-butyl)pyrrolidin-2-one is a colorless to light yellow liquid.
-Solubility: It can be dissolved in many organic solvents, such as ethanol, acetone and dimethylformamide.
-Melting point: Its melting point is approximately 107-110 degrees Celsius.
-Boiling point: Its boiling point is about 217-219 degrees Celsius.

2. Use:
- 1-(tert-butyl)pyrrolidin-2-one can be used as synthetic organic materials and intermediates. It has rich applications in the field of synthetic drugs and dyes, such as intermediates for the synthesis of many drugs, such as cephalosporins and anti-cancer drugs.

3. Preparation method: The preparation of
- 1-(tert-butyl)pyrrolidin-2-one is generally accomplished by chemical synthetic methods. The specific preparation method may include using an appropriate amount of pyrrolidone as a raw material, using an appropriate alkali or acid catalyst, heating reaction or acylation reaction to obtain the desired product.

4. Safety Information:
- 1-(tert-butyl)pyrrolidin-2-one are generally considered to be relatively safe under reasonable use. However, as with any chemical, care should be taken to avoid direct contact with the skin, eyes and respiratory tract.
-Use should comply with the correct experimental methods, such as wearing protective glasses, gloves and Laboratory atmospheric cabinets and other personal protective equipment.
-When using or storing, it should be stored in a sealed container and stored in a dry, well-ventilated place, away from fire and flammable materials.
-If taken by mistake or in contact with skin, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:45:29