N-β-(t-Butoxycarbonyl)-3-nitro-D-β-homophenylglycine
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid
CAS:
Molecular Formula: C14H18N2O6
N-β-(t-Butoxycarbonyl)-3-nitro-D-β-homophenylglycine - Names and Identifiers
N-β-(t-Butoxycarbonyl)-3-nitro-D-β-homophenylglycine - Physico-chemical Properties
| Molecular Formula | C14H18N2O6 |
| Molar Mass | 310.3 |
| Density | 1.288±0.06 g/cm3(Predicted) |
| Boling Point | 483.9±45.0 °C(Predicted) |
| pKa | 4.17±0.10(Predicted) |
| Storage Condition | 2-8°C |
N-β-(t-Butoxycarbonyl)-3-nitro-D-β-homophenylglycine - Introduction
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid is an organic compound with the chemical formula of C0.3 H₂ Nelevated. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid is a white solid with a relative molecular mass of 421.47. It has low solubility and is better soluble in conventional organic solvents such as methanol and dimethyl sulfoxide. The compounds have strong amino and acid groups.
Use:
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid is generally used as an intermediate in organic synthesis. It can be used to synthesize bioactive compounds, such as drugs, pharmaceutical intermediates and biomarkers.
Preparation Method:
The preparation of Boc-S-3-amino -3-(3-nitrophenyl) propionic acid can be achieved by the following steps:
1.3-nitroacetophenone and reactive thioesterification reagent (such as thiocyanate salt) are reacted under alkaline conditions to generate the corresponding 3-nitrophenyl malonyl sulfate.
2. Esterification reaction is carried out by Boc-S-H the above intermediate with an amino acid protecting agent under alkaline conditions to obtain the target product Boc-S-3-amino -3-(3-nitrophenyl) propionic acid.
Safety Information:
Safety information regarding Boc-S-3-amino -3-(3-nitrophenyl) propionic acid has not been clearly reported. However, as an organic compound, it can be potentially harmful to the human body. Therefore, the use and handling of the compound should follow appropriate laboratory safety practices and use appropriate personal protective equipment, such as lab gloves and goggles. In addition, the compound should be stored in a dry, dark, low-temperature environment, and away from combustibles and oxidants.
Nature:
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid is a white solid with a relative molecular mass of 421.47. It has low solubility and is better soluble in conventional organic solvents such as methanol and dimethyl sulfoxide. The compounds have strong amino and acid groups.
Use:
Boc-S-3-Amino-3-(3-nitro-phenyl)-propionic acid is generally used as an intermediate in organic synthesis. It can be used to synthesize bioactive compounds, such as drugs, pharmaceutical intermediates and biomarkers.
Preparation Method:
The preparation of Boc-S-3-amino -3-(3-nitrophenyl) propionic acid can be achieved by the following steps:
1.3-nitroacetophenone and reactive thioesterification reagent (such as thiocyanate salt) are reacted under alkaline conditions to generate the corresponding 3-nitrophenyl malonyl sulfate.
2. Esterification reaction is carried out by Boc-S-H the above intermediate with an amino acid protecting agent under alkaline conditions to obtain the target product Boc-S-3-amino -3-(3-nitrophenyl) propionic acid.
Safety Information:
Safety information regarding Boc-S-3-amino -3-(3-nitrophenyl) propionic acid has not been clearly reported. However, as an organic compound, it can be potentially harmful to the human body. Therefore, the use and handling of the compound should follow appropriate laboratory safety practices and use appropriate personal protective equipment, such as lab gloves and goggles. In addition, the compound should be stored in a dry, dark, low-temperature environment, and away from combustibles and oxidants.
Last Update：2024-04-09 21:54:55
