N-甲基伪尿苷中间体
N-甲基伪尿苷中间体
CAS: 1024616-67-8
Molecular Formula: C30H40N2O7Si
N-甲基伪尿苷中间体 - Names and Identifiers
| Name | N-甲基伪尿苷中间体 |
| Synonyms | 1024616-67-8 |
| CAS | 1024616-67-8 |
N-甲基伪尿苷中间体 - Physico-chemical Properties
| Molecular Formula | C30H40N2O7Si |
| Molar Mass | 568.73 |
N-甲基伪尿苷中间体 - Introduction
N-methyl pseudouridine intermediate is an organic compound with the chemical name 4-amino -5-chloro-N-methyl -1-(2-lipoxyethyl) pyrimidine -2-one. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Usually a colorless or white crystalline solid.
-Solubility: It may dissolve in common organic solvents (such as ethanol, chloroform, etc.), but it has poor solubility in water.
-Melting point: between 170-174 ° C.
-Chemical properties: Nucleophilic substitution reactions can occur under acidic conditions.
Use:
- N-methyl pseudouridine intermediates have important applications in the field of medicine. It is an intermediate for the synthesis of pseudo-uridine, pseudo-insulin and other nucleoside compounds. Pseudouridine has antiviral and anticancer activities, so this intermediate is of great significance in drug development.
Method:
-Starting from 5-chloro-2, 4-dinitropyridine, through the steps of Nitro initiation reaction, coupling reaction, protonation reaction and lipid oxidation, finally, the N-methyl pseudouridine intermediate was obtained. The reaction conditions and procedures will vary depending on the specific synthetic scheme.
Safety Information:
The-N-methyl pseudouridine intermediate is generally safe under reasonable use and storage conditions.
-However, because it is potentially toxic and may cause harm to the human body, appropriate protective measures need to be taken during use.
-When performing experiments, it is recommended to wear protective glasses, laboratory gloves and laboratory clothing to ensure good ventilation conditions.
-During storage, it should be placed in a dry, cool place to avoid contact with oxidants and combustibles.
-If inhaled or exposed to the compound, immediately remove from the exposed environment and receive prompt medical attention.
Nature:
-Appearance: Usually a colorless or white crystalline solid.
-Solubility: It may dissolve in common organic solvents (such as ethanol, chloroform, etc.), but it has poor solubility in water.
-Melting point: between 170-174 ° C.
-Chemical properties: Nucleophilic substitution reactions can occur under acidic conditions.
Use:
- N-methyl pseudouridine intermediates have important applications in the field of medicine. It is an intermediate for the synthesis of pseudo-uridine, pseudo-insulin and other nucleoside compounds. Pseudouridine has antiviral and anticancer activities, so this intermediate is of great significance in drug development.
Method:
-Starting from 5-chloro-2, 4-dinitropyridine, through the steps of Nitro initiation reaction, coupling reaction, protonation reaction and lipid oxidation, finally, the N-methyl pseudouridine intermediate was obtained. The reaction conditions and procedures will vary depending on the specific synthetic scheme.
Safety Information:
The-N-methyl pseudouridine intermediate is generally safe under reasonable use and storage conditions.
-However, because it is potentially toxic and may cause harm to the human body, appropriate protective measures need to be taken during use.
-When performing experiments, it is recommended to wear protective glasses, laboratory gloves and laboratory clothing to ensure good ventilation conditions.
-During storage, it should be placed in a dry, cool place to avoid contact with oxidants and combustibles.
-If inhaled or exposed to the compound, immediately remove from the exposed environment and receive prompt medical attention.
Last Update：2024-04-09 20:45:29
