N-苄氧羰基-L-谷氨酸1-甲酯

N-苄氧羰基-L-谷氨酸1-甲酯 - Names and Identifiers

Name	4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name)
Synonyms	Z-Glu-OMe Z-L-glutaMic acid beta-Methyl ester N-BENZYLOXYCARBONYL-L-GLUTAMIC ACID 1-METHYL ESTER N-ALPHA-CARBOBENZOXY-L-GLUTAMIC ACID ALPHA-METHYL ESTER N-ALPHA-BENZYLOXYCARBONYL-L-GLUTAMIC-ACID ALPHA-METHYL ESTER L-GlutaMic acid,N-[(phenylMethoxy)carbonyl]-, 1-Methyl ester (4S)-4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid [({[(1S)-3-carboxylato-1-(methoxycarbonyl)propyl]carbamoyl}oxy)methyl]benzene 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) (4S)-4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) N-Carbobenzoxy-L-glutamic Acid 1-Methyl Ester1-Methyl N-Cbz-L-glutamateN-Cbz-L-glutamic Acid 1-Methyl EsterZ-Glu-OMe
CAS	5672-83-3
InChI	InChI=1/C14H17NO6/c1-20-13(18)11(7-8-12(16)17)15-14(19)21-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,15,19)(H,16,17)

N-苄氧羰基-L-谷氨酸1-甲酯 - Physico-chemical Properties

Molecular Formula	C14H17NO6
Molar Mass	295.29
Density	1.2393 (rough estimate)
Melting Point	68-70°C(lit.)
Boling Point	436.98°C (rough estimate)
Flash Point	262.6°C
Vapor Presure	3.01E-11mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
BRN	2567599
pKa	4.48±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.4365
MDL	MFCD00083278

N-苄氧羰基-L-谷氨酸1-甲酯 - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29242990

N-苄氧羰基-L-谷氨酸1-甲酯 - Introduction

4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) is a compound whose chemical structure is C17H21NO6. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) is present as a white solid.
-Solubility: It has low solubility in water and is soluble in organic solvents such as ethanol, dichloromethane, etc.

Use:
-Chemical research: 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) can be used in organic synthesis reactions, such as peptide synthesis, esterification reactions, etc.

Preparation Method:
4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) can be prepared by common organic synthesis reactions, such as the following steps:
1. N-benzyl-L-glutamic acid is reacted with formic acid to generate N-benzyl-L-glutamic acid 1-methyl ester.
2. Reaction of N-benzyl-L-glutamic acid 1-methyl ester with benzyl chloromethyl ether under appropriate conditions yields 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name).

Safety Information:
Because 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid (non-preferred name) has not been widely studied and used, its detailed security information may be limited. However, like many chemicals, it can be irritating and toxic. Appropriate laboratory safety practices and proper handling and storage of chemicals should be followed during handling and use. Before use, it is best to refer to the relevant chemical literature and safety data sheets for detailed safety information.

Last Update：2024-04-09 21:32:42