N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt
CAS: 16966-07-7
Molecular Formula: C28H46N2O5
N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐 - Names and Identifiers
| Name | N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt |
| Synonyms | Z-Thr(tBu)-OH·DCHA Z-Thr(Tbu)-Oh Dcha Z-Thr(tBu)-OH.DCHA Z-Thr(But)-OH*DCHA Z-THR(TBU)-OH DCHA SALT Cbz-DL-Thr(tBu)-OH DCHA Z-THREONINE(TBU)-OH DCHA Z-T-BUTYL-L-THREONINE DCHA SALT Z-Thr(tBu)-OH dicyclohexylamine salt Z-O-tert.butyl-L-threoninedicyclohexylamine salt Z-O-tert·butyl-L-threoninedicyclohexylamine salt N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt N-Benzyloxycarbonyl-O-tert-butyl-L-threonine dicyclohexylamine N-benzyloxycarbonyl-O-tert-butyl-L-threonine, compound with dicyclohexylamine |
| CAS | 16966-07-7 |
| EINECS | 241-040-0 |
| InChI | InChI=1/C16H23NO5.C12H23N/c1-11(22-16(2,3)4)13(14(18)19)17-15(20)21-10-12-8-6-5-7-9-12;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19);11-13H,1-10H2/t11?,13-;/m0./s1 |
N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐 - Physico-chemical Properties
| Molecular Formula | C28H46N2O5 |
| Molar Mass | 490.68 |
| Melting Point | 143-147°C |
| Boling Point | 636.3°C at 760 mmHg |
| Flash Point | 338.6°C |
| Vapor Presure | 4.58E-17mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | Inert atmosphere,2-8°C |
N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐 - Risk and Safety
| WGK Germany | 3 |
N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐 - Introduction
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is an organic compound with the following properties:
1. Appearance: white or white crystal powder.
2. Solubility: soluble in organic solvents, such as methanol and ethanol, almost insoluble in water.
3. Melting point: about 160-165 ° C.
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is often used as a synthetic intermediate for the following purposes:
1. Impedance agent: In synthetic drugs, it is often used to prepare potential amino acid-based drugs.
2. Protecting group: it can be used to protect amino acids in organic synthesis to prevent side reactions in the reaction process.
3. Drug formulation: It can be used as a part of the drug formulation to improve its solubility and stability.
The preparation method of N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is as follows:
1. In the presence of sulfur hexachloride, tert-butoxycarbonylchloromethyl is reacted with L-threonine to obtain N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride.
2. N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride is reacted with dicyclohexylamine under alkaline conditions to generate the N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt.
Regarding safety information, N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is a compound, you need to pay attention to the following matters during operation:
1. Avoid inhalation: Wear a suitable protective mask to prevent dust, smoke or gas from entering the respiratory system.
2. Avoid contact with skin and eyes: Use protective gloves and goggles to protect the skin and eyes to reduce direct contact of the compound to the skin and eyes.
3. Pay attention to the fire Source: avoid the compound from contact with the fire source or electrostatic discharge to prevent fire and explosion.
4. Storage conditions: should be stored in a dry, cool place, away from open flames and oxidants.
It should be emphasized that the information provided above is for reference only. The specific use and operation should follow the safety operation guidelines and laboratory operation specifications of relevant chemicals.
1. Appearance: white or white crystal powder.
2. Solubility: soluble in organic solvents, such as methanol and ethanol, almost insoluble in water.
3. Melting point: about 160-165 ° C.
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is often used as a synthetic intermediate for the following purposes:
1. Impedance agent: In synthetic drugs, it is often used to prepare potential amino acid-based drugs.
2. Protecting group: it can be used to protect amino acids in organic synthesis to prevent side reactions in the reaction process.
3. Drug formulation: It can be used as a part of the drug formulation to improve its solubility and stability.
The preparation method of N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is as follows:
1. In the presence of sulfur hexachloride, tert-butoxycarbonylchloromethyl is reacted with L-threonine to obtain N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride.
2. N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride is reacted with dicyclohexylamine under alkaline conditions to generate the N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt.
Regarding safety information, N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is a compound, you need to pay attention to the following matters during operation:
1. Avoid inhalation: Wear a suitable protective mask to prevent dust, smoke or gas from entering the respiratory system.
2. Avoid contact with skin and eyes: Use protective gloves and goggles to protect the skin and eyes to reduce direct contact of the compound to the skin and eyes.
3. Pay attention to the fire Source: avoid the compound from contact with the fire source or electrostatic discharge to prevent fire and explosion.
4. Storage conditions: should be stored in a dry, cool place, away from open flames and oxidants.
It should be emphasized that the information provided above is for reference only. The specific use and operation should follow the safety operation guidelines and laboratory operation specifications of relevant chemicals.
Last Update：2024-04-09 20:02:46
Supplier List
Spot supply
Product Name: Z-Thr(tBu)-OH.DCHA Visit Supplier Webpage Request for quotationCAS: 16966-07-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Z-Thr(tBu)-OH.DCHA Visit Supplier Webpage Request for quotationCAS: 16966-07-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Z-THR(TBU)-OH DCHA Visit Supplier Webpage Request for quotation
CAS: 16966-07-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 16966-07-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Z-Thr(tBu)-OH.DCHA Visit Supplier Webpage Request for quotationCAS: 16966-07-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Z-Thr(tBu)-OH.DCHA Visit Supplier Webpage Request for quotationCAS: 16966-07-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Z-THR(TBU)-OH DCHA Visit Supplier Webpage Request for quotation
CAS: 16966-07-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 16966-07-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
N-苄氧羰基-O-叔丁基-L-苏氨酸二环己胺盐
L-酪氨酸异丙酯盐酸盐
Menthyl ethoxyacetate
DICYCLOHEXYLAMINEHYDROCHLORIDE
FMOC-5-AMINOVALERIC ACID
2-BroMo-5-hydrazinylpyrazine
5-羟基-L-赖氨酸
1-甲基-4,6-二氢-1H-吡咯并[3,4-C]吡唑-5-羧酸叔-丁基酯
Chitosan oligosaccharide (COS)
Agsol Ex 2
L-酪氨酸异丙酯盐酸盐
Menthyl ethoxyacetate
DICYCLOHEXYLAMINEHYDROCHLORIDE
FMOC-5-AMINOVALERIC ACID
2-BroMo-5-hydrazinylpyrazine
5-羟基-L-赖氨酸
1-甲基-4,6-二氢-1H-吡咯并[3,4-C]吡唑-5-羧酸叔-丁基酯
Chitosan oligosaccharide (COS)
Agsol Ex 2