N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide
YYA-021
CAS: 144217-65-2
Molecular Formula: C18H27N3O2
N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide - Names and Identifiers
| Name | YYA-021 |
| Synonyms | YYA-021 CS-2313 YYA-021 (YYA 021 N1-(2,2,6,6-tetraMethylpiperidin-4-yl)-N2-p-tolyloxalaMide N-(2,2,6,6-Tetramethyl-piperidin-4-yl)-N'-p-tolyl-oxalamide N-(4-Methylphenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide Ethanediamide, N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)- |
| CAS | 144217-65-2 |
N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide - Physico-chemical Properties
| Molecular Formula | C18H27N3O2 |
| Molar Mass | 317.43 |
| Density | 1.11±0.1 g/cm3(Predicted) |
| Solubility | 10 mM in DMSO |
| pKa | 11.61±0.70(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | YYA-021 enhance the neutralization susceptibility of apes-human immunodeficiency virus (HIV-1) carrying MNA envelope isolated from clade B clinical human immunodeficiency virus type I (SHIV). |
| In vivo study | In rats and rhesus monkeys, YYA-021 (I. V.) has a moderate Half-Life, broad tissue distribution, and relatively high volume distribution. |
N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.15 ml | 15.752 ml | 31.503 ml |
| 5 mM | 0.63 ml | 3.15 ml | 6.301 ml |
| 10 mM | 0.315 ml | 1.575 ml | 3.15 ml |
| 5 mM | 0.063 ml | 0.315 ml | 0.63 ml |
Last Update：2024-01-02 23:10:35
N1-(4-Methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide - Reference Information
| biological activity | YYA-021 is an HIV entry inhibitor that mimics CD4, competitively inhibiting the interaction between gp120 and CD4. |
| Target | Value |
Last Update：2024-04-09 20:49:11
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Product Name: YYA-021 Visit Supplier Webpage Request for quotationCAS: 144217-65-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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