N2-(Benzyloxycarbonyl)-L-threoninamide

N2-(Benzyloxycarbonyl)-L-threoninamide - Names and Identifiers

Name	Z-Thr-NH2
Synonyms	CBZTA Z-Thr-NH2 cbz-l-threoninamide CBZ-L-THREONINE AMIDE N-Carbobenzyloxy-L-threoninamide N-Benzyloxycarbonyl-L-Threoninamide N2-(Benzyloxycarbonyl)-L-threoninamide benzyl (1-carbamoyl-2-hydroxypropyl)carbamate Benzyl (2R,3S)-(1-carbamoyl-2-hydroxypropyl)carbamate (1R,2S)-1-benzyl-1-carbamoyl-2-hydroxypropyl carbamate benzyl [R-(R,S)]-(1-carbamoyl-2-hydroxypropyl)carbamate [(2R,3S)-1-Amino-3-hydroxy-1-oxo-2-(phenylmethyl)butan-2-yl] carbamate
CAS	49705-98-8
EINECS	256-436-9
InChI	InChI=1/C12H16N2O4/c1-8(15)12(10(13)16,18-11(14)17)7-9-5-3-2-4-6-9/h2-6,8,15H,7H2,1H3,(H2,13,16)(H2,14,17)/t8-,12+/m0/s1

N2-(Benzyloxycarbonyl)-L-threoninamide - Physico-chemical Properties

Molecular Formula	C12H16N2O4
Molar Mass	252.27
Density	1.263±0.06 g/cm3(Predicted)
Melting Point	82-83 °C
Boling Point	508.4±50.0 °C(Predicted)
Flash Point	292.9°C
Solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig
Vapor Presure	2.07E-13mmHg at 25°C
Appearance	Powder
Color	White
BRN	2335408
pKa	10.96±0.46(Predicted)
Storage Condition	-20°C
Refractive Index	1.58

N2-(Benzyloxycarbonyl)-L-threoninamide - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

N2-(Benzyloxycarbonyl)-L-threoninamide - Introduction

(Z-Thr-NH2) is an organic compound with the chemical name Z-Thr-NH2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless solid
-Molecular formula: C12H16N2O4
-Molecular weight: 252.27g/mol
-Solubility: Soluble in organic solvents such as methanol, dichloromethane
-Melting point: about 150-155°C

Use:
- (Z-Thr-NH2) can be used as an intermediate for the synthesis of peptides or proteins, and is commonly used in solid phase synthesis and liquid phase synthesis. It can be used to prepare polypeptides, drugs, antibodies, bioactive peptides, etc. It plays an important role in medical research and pharmaceutical industry.

Preparation Method:
- (Z-Thr-NH2) can be prepared by a variety of methods, common methods include peptide synthesis, esterification, etc. The specific preparation method can be selected according to the specific reaction conditions and the desired product.

Safety Information:
- (Z-Thr-NH2) The relevant safety information is limited, pay attention to follow the laboratory safety procedures. The compound may cause irritation to the skin, eyes and respiratory tract, and appropriate protective measures should be taken, such as wearing gloves, glasses and masks. To avoid inhalation, it is best to operate in a well-ventilated area and avoid direct contact with skin and eyes. In the event of any accident, seek medical attention immediately and provide compound information to the doctor for reference.

In addition, the storage and handling of chemicals need to comply with relevant laws and regulations. It is recommended to operate in a special chemical laboratory, and properly store and dispose of chemical waste. When using (Z-Thr-NH2), please follow the relevant safety instructions and consult a professional.

Last Update：2024-04-09 21:32:41