N3-PEG7-NH2 - Names and Identifiers
N3-PEG7-NH2 - Physico-chemical Properties
Molecular Formula | C16H34N4O7
|
Molar Mass | 394.46376 |
Appearance | Morphological solid or viscous liquid |
Storage Condition | -20°C |
Physical and Chemical Properties | Bioactive Azido-PEG7-amine is a non-cleavable 7-unit PEG-ADC linker used in the synthesis of antibody-coupled drugs (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis. |
N3-PEG7-NH2 - Upstream Downstream Industry
N3-PEG7-NH2 - Introduction
Amino-PEG8-azide(Amino-PEG8-azide) is a chemical compound whose molecular structure contains an amino group (-NH2), eight ethylene glycol units (PEG8), and an azide group (-N3).
Nature:
Amino-PEG8-azide is a colorless or light yellow liquid, soluble in water and some organic solvents such as methanol and dimethyl sulfoxide. The compound is a relatively stable reagent.
Use:
Amino-PEG8-azide are often used as cross-linking reagents and coupling agents in the fields of biology and chemistry. It can react with other compounds to generate new functional molecules, such as synthetic polymers, drug delivery carriers, nanoparticles, etc. The coupling reaction can be achieved by click chemistry.
Method:
Amino-PEG8-azide can be prepared by methods of synthetic organic chemistry. The specific synthetic route can be optimized according to the requirements and conditions.
Safety Information:
When using Amino-PEG8-azide, follow regular laboratory safety practices. The compound belongs to the first class of dangerous goods, has a certain toxicity. Wear appropriate personal protective equipment, such as laboratory gloves, goggles and laboratory coats, and operate in a well-ventilated environment. Avoid direct contact with skin and eyes. Relevant safety codes and regulations should be followed during handling and disposal.
Last Update:2024-04-09 02:00:50