N3-PEG8-CH2CH2COONHS

Name	Azido-PEG8-NHS ester
Synonyms	N3-PEG8-SPA N3-PEG8-NHS AZIDO-PEG8-NHS N3-PEG8-CH2CH2COONHS Azido-PEG8-NHS ester Azido-dPEG(R)8-NHS ester N3-PEG8-CH2CH2COONHS Ester N3-PEG8-NHS Ester,Azido-PEG8-NHS ester
CAS	1204834-00-3

Molecular Formula	C23H40N4O12
Molar Mass	564.5833
Appearance	solid or viscous liquid
Storage Condition	-20°C
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

biological activity	Azido-PEG8-NHS ester is a degradable (cleavable) 8-unit PEG-containing ADC linker that can be used to synthesize antibody-coupled drugs (ADC). Azido-PEG8-NHS ester is also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used to synthesize PROTAC molecules.
target	PEGs Alkyl/ether Cleavable
in vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Last Update：2024-04-09 20:52:54

Product Name: Azido-PEG8-NHS ester Visit Supplier Webpage Request for quotation
CAS: 1204834-00-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Azido-PEG8-NHS ester Visit Supplier Webpage Request for quotation
CAS: 1204834-00-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

N3-PEG8-CH2CH2COONHS

N3-PEG8-CH2CH2COONHS Request for Quotation