NALPHA-BOC-NEPSILON-Z-L-LYSINE
na-T-boc-N-epsilon-cbz-L-lysine*free acid
CAS: 2389-45-9
Molecular Formula: C19H28N2O6
NALPHA-BOC-NEPSILON-Z-L-LYSINE - Names and Identifiers
NALPHA-BOC-NEPSILON-Z-L-LYSINE - Physico-chemical Properties
| Molecular Formula | C19H28N2O6 |
| Molar Mass | 380.44 |
| Density | 1.176±0.06 g/cm3(Predicted) |
| Melting Point | 75.0 to 79.0 °C |
| Boling Point | 587.0±50.0 °C(Predicted) |
| Flash Point | 308.8°C |
| Solubility | almost transparency in Acetic acid |
| Vapor Presure | 1.26E-14mmHg at 25°C |
| Appearance | White powder |
| Color | White to Almost white |
| BRN | 1917222 |
| pKa | 3.99±0.21(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | -8 ° (C=2.5, AcOH) |
| MDL | MFCD00065584 |
| Use | N-Boc-N "-Cbz-L-lysine is an N-terminal protected amino acid used in solid phase peptide synthesis (SPPS) to make the peptide contain Nepsilon protected lysyl side chains. |
NALPHA-BOC-NEPSILON-Z-L-LYSINE - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 2924 29 70 |
NALPHA-BOC-NEPSILON-Z-L-LYSINE - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| preparation | to (2S)-6-amino -2-(tert-butoxycarbonylamino) hexanoic acid (100.00g,406.01mmol,1.00 when amount), NaHCO3(102.33g,1.22mol,3.00 equivalent) CbzOSu(101.19g,406.01mmol,1.00 equivalent) is added to the solution in THF(1000mL) and H2O (1000mL) at 0 ℃. The mixture was then stirred at 30°C for 16h. The mixture was adjusted with 1N HCl to pH = 5-6, extracted with EA(600mL × 3), dried with Na2SO4, and concentrated to obtain a yellow oily N-Boc-N-Cbz-L-lysine (142.00g,373.26mmol,91.9% yield). |
| Uses | N-Boc-N '-Cbz-L-lysine is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make the peptide contain Nepsilon protected lysyl side chains. |
Last Update：2024-04-09 21:11:58
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