NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine
N(alpha)-boc-N(omega)-tosyl-D-arginine
CAS: 61315-61-5
Molecular Formula: C18H28N4O6S
NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine - Names and Identifiers
| Name | N(alpha)-boc-N(omega)-tosyl-D-arginine |
| Synonyms | _ Boc-D-Arg(Tos)-OH (Tert-Butoxy)Carbonyl D-Arg(Tos)-OH N(alpha)-boc-N(omega)-tosyl-D-arginine Boc-D-Arg(Tos)-OH N-α-Boc-N-ω-tosyl-D-arginine NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine N-ALPHA-T-BUTYLOXYCARBONYL-N-GAMMA-(4-TOLUOLSULFONYL)-D-ARGININE (2R)-2-(tert-butoxycarbonylamino)-5-[(N-(p-tolylsulfonyl)carbamimidoyl)amino]pentanoic acid (2R)-2-{[(tert-butoxy)carbonyl]amino}-5-[N'-(4-methylbenzenesulfonyl)carbamimidamido]pentanoic acid |
| CAS | 61315-61-5 |
| InChI | InChI=1/C18H28N4O6S/c1-12-7-9-13(10-8-12)29(26,27)22-16(19)20-11-5-6-14(15(23)24)21-17(25)28-18(2,3)4/h7-10,14H,5-6,11H2,1-4H3,(H,21,25)(H,23,24)(H3,19,20,22)/t14-/m1/s1 |
NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine - Physico-chemical Properties
| Molecular Formula | C18H28N4O6S |
| Molar Mass | 428.5 |
| Density | 1.31±0.1 g/cm3(Predicted) |
| Melting Point | 90-100°C |
| Specific Rotation(α) | -5 º (c=1,EtOH) |
| BRN | 4726241 |
| pKa | 3.95±0.21(Predicted) |
| Storage Condition | -15°C |
| Refractive Index | 1.575 |
| MDL | MFCD00038260 |
| Physical and Chemical Properties | Melting point 90-100°C specific optical rotation -5 ° (c = 1,EtOH) |
NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29350090 |
| Hazard Class | IRRITANT |
NALPHA-tert-Butoxycarbonyl-NOMEGA-(4-toluenesulfonyl)-D-arginine - Introduction
N(alpha)-boc-N(omega)-tosyl-D-arginine is an organic compound with the chemical formula N(alpha)-boc-N(omega)-tosyl-D-arginine.
Nature:
N(alpha)-boc-N(omega)-tosyl-D-arginine is a white crystalline powder with good solubility. It is a reagent for protecting amino acids, which is often used for the protection of amino acids and functional groups in organic synthesis to avoid unnecessary reactions.
Use:
N(alpha)-boc-N(omega)-tosyl-D-arginine are mainly used in the field of peptide synthesis. It can be used as an amino protection reagent for the synthesis of peptides, proteins and peptide drugs. By introducing a BOC protecting group on the arginine amino group, the amino group can be prevented from undesired reactions during the synthesis.
Preparation Method:
The method of preparing N(alpha)-boc-N(omega)-tosyl-D-arginine is relatively complicated and requires the use of chemical reagents and equipment, so it is best to synthesize it in a professional laboratory. The general procedure involves reacting p-methylbenzenesulfonyl chloride with D-arginine and reacting the resulting product with BOC acid chloride.
Safety Information:
N(alpha)-boc-N(omega)-tosyl-D-arginine has no obvious toxicity to human health, but it is an organic synthetic reagent, so it is necessary to pay attention to personal protective measures during operation, such as wearing gloves, goggles and protective clothing. At the same time, avoid contact with skin or eyes, and maintain operations in a well-ventilated laboratory environment. In case of inhalation or ingestion, seek medical attention immediately.
Nature:
N(alpha)-boc-N(omega)-tosyl-D-arginine is a white crystalline powder with good solubility. It is a reagent for protecting amino acids, which is often used for the protection of amino acids and functional groups in organic synthesis to avoid unnecessary reactions.
Use:
N(alpha)-boc-N(omega)-tosyl-D-arginine are mainly used in the field of peptide synthesis. It can be used as an amino protection reagent for the synthesis of peptides, proteins and peptide drugs. By introducing a BOC protecting group on the arginine amino group, the amino group can be prevented from undesired reactions during the synthesis.
Preparation Method:
The method of preparing N(alpha)-boc-N(omega)-tosyl-D-arginine is relatively complicated and requires the use of chemical reagents and equipment, so it is best to synthesize it in a professional laboratory. The general procedure involves reacting p-methylbenzenesulfonyl chloride with D-arginine and reacting the resulting product with BOC acid chloride.
Safety Information:
N(alpha)-boc-N(omega)-tosyl-D-arginine has no obvious toxicity to human health, but it is an organic synthetic reagent, so it is necessary to pay attention to personal protective measures during operation, such as wearing gloves, goggles and protective clothing. At the same time, avoid contact with skin or eyes, and maintain operations in a well-ventilated laboratory environment. In case of inhalation or ingestion, seek medical attention immediately.
Last Update：2024-04-09 21:32:42
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CAS: 61315-61-5
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Mobile: 18021002903
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