NANA
N-Acetylneuraminic acid
CAS: 131-48-6
Molecular Formula: C11H19NO9
NANA - Names and Identifiers
NANA - Physico-chemical Properties
| Molecular Formula | C11H19NO9 |
| Molar Mass | 309.27 |
| Density | 1.3580 (rough estimate) |
| Melting Point | 184-186 °C |
| Boling Point | 449.56°C (rough estimate) |
| Specific Rotation(α) | -32 º (c=2,water) |
| Flash Point | 440.7°C |
| Water Solubility | 50 g/L (20 ºC) |
| Solubility | Soluble in water, slightly soluble in ethanol, insoluble in ether |
| Vapor Presure | 5.5E-30mmHg at 25°C |
| Appearance | White or white-like crystalline powder |
| Color | White to Off-White |
| Merck | 14,8484 |
| BRN | 1716283 |
| pKa | 2.41±0.54(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Air Sensitive |
| Refractive Index | -32 ° (C=1, H2O) |
| MDL | MFCD00006620 |
| Physical and Chemical Properties | Melting point 184-186°C specific optical rotation -32 ° (c = 2,water) water-soluble 50g/L (20°C) |
| Use | This product is for scientific research only and shall not be used for other purposes. |
NANA - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-23 |
| TSCA | Yes |
| HS Code | 29329970 |
| Hazard Note | Irritant |
NANA - Reference
| Reference Show more | 1. [IF=7.1] Rui Duan et al."Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein."Sensor Actuat B-Chem. 2021 Mar;330:129310 2. [IF=6.057] Yi Luo et al."PEGylation of boronate-affinity-oriented surface imprinting magnetic nanoparticles with improved performance."Talanta. 2022 Feb;238:122992 3. [IF=1.913] Dai Yuwei et al."Study on sialic acid binding state in stewed bird's nest and optimization of enzymatic extraction of free and oligosaccharide-bound sialic acid."J Aoac Int. 2021 Aug;: |
NANA - Introduction
Both sialic acid and neuraminic acid are usually broadly called neuraminic acid conjugates. This product is a characteristic component of the cell wall of gram-negative bacteria. Through Toll-like receptor 4(TLR4), this product can partially stimulate innate immune cells with lipid A. Studies have found that N-acetylneuraminic acid is usually the terminal sugar of cell surface glycoproteins. Cell surface glycoproteins play an important role in cell recognition, cell interaction and cell adhesion. Membrane glycoproteins also play an important role in tumor growth and metastasis.
Last Update：2022-10-16 17:13:12
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