NEOXANTHIN(SH)
NEOXANTHIN
CAS: 14660-91-4
Molecular Formula: C40H56O4
NEOXANTHIN(SH) - Names and Identifiers
| Name | NEOXANTHIN |
| Synonyms | NEOXANTHIN cis-Neoxanthin NEOXANTHIN(SH) 9'-cis-Neoxanthin (3S,3'S,5R,5'R,6R,6'S,9'Z)-6,7-Didehydro-5',6'-epoxy-5,5',6,6'-tetrahydro-β,β-caroten-3,3',5-triol (3S,3'S,5R,5'R,6R,6'S,9'Z)-6,7-Didehydro-5',6'-epoxy-5,5',6,6'-tetrahydro-β,β-carotene-3,3',5-triol (3S,3'S,5R,5'R,6S,6'R,9Z)-5,6-Epoxy-6',7'-didehydro-5,6,5',6'-tetrahydro-β,β-carotene-3,3',5'-triol (3S,3'S,5R,5'R,6R,6'S,9'-CIS)-6,7-DIDEHYDRO-5',6'-EPOXY-5',6'-DIHYDRO-Β,Β-CAROTENE-3,3',5(6H)-TRIOL SOLUTION IN ETHANOL (1R,3S)-6-[(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenylidene]-1,5,5-trimethyl-cyclohexane-1,3-diol |
| CAS | 14660-91-4 |
NEOXANTHIN(SH) - Physico-chemical Properties
| Molecular Formula | C40H56O4 |
| Molar Mass | 600.88 |
| Density | 1.06±0.1 g/cm3(Predicted) |
| Boling Point | 733.3±60.0 °C(Predicted) |
| Maximum wavelength(λmax) | ['λ: 435-439 nm Amax'] |
| pKa | 14.65±0.60(Predicted) |
| Storage Condition | -20°C |
| In vitro study | Neoxanthin (20 μM; 72 h) treatment significantly reduces cell viability to 10.9% for PC-3 cells, 15.0% for DU 145 cells, and nearly zero for LNCaP cells, respectively. Neoxanthin strongly inhibits cell growth by suppressing DNA synthesis in C3H10T1/2 cells. In photosynthetic organisms, Neoxanthin is the essential component of both the photosystem I (PSI) and photosystem II (PSII) reaction centers of oxygenic photosynthetic apparatus. |
| In vivo study | The gastrointestinal metabolism of Neoxanthin in mice is investigated. Two hours after the oral administration of Neoxanthin (40 nmol/mouse), Neoxanthin is found in the plasma and livers of mice. The concentrations of Neoxanthin is 13.6-9.0 nM in plasma, and 7.3 3.6 pmol/g in liver, respectively. (R/S)-Neochrome is also found in the small intestinal contents of Neoxanthin-administered mice. |
NEOXANTHIN(SH) - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29109000 |
NEOXANTHIN(SH) - References
| biological activity | nexanthin is a major lutein carotenoid found in dark green leafy vegetables, is a precursor of the plant hormone abscisic acid. Neoxanthin is a potent antioxidant and light-harvesting pigment that induces apoptosis and has anti-cancer effects. |
Last Update：2024-04-09 21:54:55
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