NH2-PEG-Tert(叔丁酯) - Names and Identifiers
NH2-PEG-Tert(叔丁酯) - Physico-chemical Properties
NH2-PEG-Tert(叔丁酯) - Introduction
NH2-PEG-Tert (tert-butyl ester)(NH2-PEG-Tert (tert-butyl ester)), is a polyethylene glycol (PEG) modified compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- NH2-PEG-Tert (tert-butyl ester) is an organic compound with high solubility and chemical stability.
-It is based on a polyethylene glycol (PEG) chain with a protected amino (NH2) and tert-butyl ester (Tert (tert-butyl ester)) modification group attached to the end.
-Its molecular weight can be customized according to needs, usually between thousands to tens of thousands of Daltons.
Use:
- NH2-PEG-Tert (tert-butyl ester) has a wide range of applications in the biomedical field.
-It can be used as a raw material for drug delivery systems to increase the solubility, stability and bioavailability of the drug by combining the drug with it.
-It can also be used as a surface modifier, attaching it to nanoparticles, proteins and other biological macromolecules to enhance their stability and biocompatibility.
Preparation Method:
- NH2-PEG-Tert (tert-butyl ester) is usually prepared by chemical synthesis.
-First, polyethylene glycol (PEG) is reacted with an activator to introduce a tert-butyryl chloride (tert-butyryl anhydride) group.
-Then, the protected amino group is reacted with PEG-Tert (tert-butyl ester) to protect the amino terminus.
-Finally, by removing the protecting group, the NH2-PEG-Tert (tert-butyl ester) is obtained.
Safety Information:
-Under normal conditions of use, NH2-PEG-Tert (tert-butyl ester) is relatively safe in general laboratory operations.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, when touching or handling this compound.
-When storing and handling the compound, care should be taken to prevent it from being exposed to moisture and humid environments to avoid reducing its stability.
-During use, comply with the correct use and handling of chemicals and dispose of them properly.
Last Update:2024-04-09 21:01:54