NH2-PEG4-CH2COOH
Amino-PEG4-CH2COOH
CAS: 195071-49-9
Molecular Formula: C10H21NO6
NH2-PEG4-CH2COOH - Names and Identifiers
NH2-PEG4-CH2COOH - Physico-chemical Properties
| Molecular Formula | C10H21NO6 |
| Molar Mass | 251.28 |
| Density | 1.156±0.06 g/cm3(Predicted) |
| Boling Point | 397.6±32.0 °C(Predicted) |
| pKa | 3.39±0.10(Predicted) |
| Storage Condition | 2-8°C，避光，干燥，密封 |
| MDL | MFCD27977508 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
NH2-PEG4-CH2COOH - Reference Information
| biological activity | Amino-PEG4-CH2COOH is a PROTAC linker belonging to the PEG class. Amino-PEG4-CH2COOH can be used for the synthesis of PROTAC molecules. Amino-PEG4-CH2COOH is also a non-cleavable ADC linker containing 4 units of PEG and can be used to synthesize antibody-conjugated drugs (ADCS). |
Last Update：2024-04-09 19:05:17
