NHS-PEG-SH - Names and Identifiers
NHS-PEG-SH - Physico-chemical Properties
NHS-PEG-SH - Introduction
NHS-PEG-SH(NHS-PEG-SH) is a commonly used functionalized polymer compound. Its properties are as follows:
-Basic properties: NHS-PEG-SH is a polymer compound whose structure contains both active ester (NHS) and thiol (SH) groups. This gives it active chemical reactivity and thiophilic properties.
-Uses: NHS-PEG-SH are widely used in drug delivery systems, protein modification and modification, and biosensors. It can be used as a carrier of drug molecules, bind to drug molecules through active ester groups, and use the hydrophilicity of PEG and the reactivity of thiol groups to adjust the solubility, stability and drug release kinetics of drugs.
-Preparation Method: NHS-PEG-SH are generally prepared by reacting polyethylene glycol (PEG) with an active ester (NHS) and a thiol (SH) compound to form an ester bond and a sulfur bond. During the preparation process, attention should be paid to the reaction temperature, reaction time and reactant ratio to ensure the selectivity and yield of the reaction.
-Safety information: When using the NHS-PEG-SH, care should be taken to avoid contact with skin and eyes. Personal protective equipment should be worn and operated in a well-ventilated laboratory environment. Care should be taken to avoid inhalation or ingestion, and to avoid mixing with strong oxidants and acids. Before use, you should carefully read the relevant safety data sheets and operating instructions, and follow the correct operating procedures and precautions.
Last Update:2024-04-09 19:06:00