NICARBAZINE
nicarbazin
CAS: 330-95-0
Molecular Formula: C19H18N6O6
NICARBAZINE - Names and Identifiers
| Name | nicarbazin |
| Synonyms | mk75 nicarb NICARBAZIN nicarbazin NICARBAZINE Nicarbazine NICARBAZINUM Perfume for benzin No. 63 1,3-Bis(4-nitrophenyl)urea-4,6-dimethylpyrimidin-2-ol N,N'-BIS(4-NITROPHENYL)UREA COMPOUND WITH 4,6-DIMETHYL-2-PYRIMIDINONE n,n'-bis(4-nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone |
| CAS | 330-95-0 |
| EINECS | 206-359-1 |
| InChI | InChI=1/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9) |
NICARBAZINE - Physico-chemical Properties
| Molecular Formula | C19H18N6O6 |
| Molar Mass | 426.38 |
| Density | 1.4663 (rough estimate) |
| Melting Point | 265-267 °C |
| Boling Point | 541.86°C (rough estimate) |
| Flash Point | 204.7°C |
| Solubility | Non-hygroscopic, insoluble in water, ethanol, chloroform and ether, slightly soluble in dimethylformamide |
| Vapor Presure | 4.32E-07mmHg at 25°C |
| Appearance | Pale yellow crystalline powder |
| Color | Yellow to Dark Yellow |
| Storage Condition | 0-6°C |
| Refractive Index | 1.6000 (estimate) |
| Physical and Chemical Properties | Light yellow crystalline powder, odorless. Melting point 265-275 °c (decomposition). Non-hygroscopic, insoluble in water, ethanol, chloroform and ether, micro-soluble in dimethylformamide. And water grinding will slowly decompose, in dilute acid decomposition faster. |
| Use | For the treatment of chicken coccidiosis Coccidiosis |
| In vivo study | Nicarbazin does not adversely affect the development of immunity or resistance to re-infection with E. acervulina oocysts. |
NICARBAZINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | FE0900000 |
| HS Code | 38249099 |
NICARBAZINE - Nature
Open Data Verified Data
light yellow crystalline powder, odorless. Melting point 265~275 °c (decomposition). Non-hygroscopic, insoluble in water, ethanol, chloroform and ether, micro-soluble in dimethylformamide. And water grinding will slowly decompose, in dilute acid decomposition faster.
Last Update：2024-01-02 23:10:35
NICARBAZINE - Preparation Method
Open Data Verified Data
obtained by cyclization of 4,4 '-p-nitrodiphenyl urea, acetylacetone and urea. Alternatively prepared from 4.4 '-p-nitrodiphenyl urea with 2-hydroxy -4,6-= methylpyrimidine.
Last Update：2022-01-01 10:11:10
NICARBAZINE - Use
Open Data Verified Data
has the advantages of high efficiency, low toxicity, stable performance, small drug resistance and so on. It has a good preventive effect on chicken cecum coccidia, pile-type eicycosis, giant eicycosis and eicycosis. It is effective and safe for the second generation merozoite of coccidia. For the prevention of coccidiosis in chickens and turkeys.
Last Update：2022-01-01 10:11:10
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