Name | NLG919 |
Synonyms | NLG919 CS-820 NLG-919 GDC 0919 IDO INHIBITOR 5-(2-Cyclohexyl-2-hydroxyethyl)-5H-imidazo[5,1-a]isoindole |
CAS | 1402836-58-1 |
EINECS | 1592732-453-0 |
Molecular Formula | C18H22N2O |
Molar Mass | 282.38 |
Density | 1.27±0.1 g/cm3(Predicted) |
Melting Point | 143 - 146°C |
Boling Point | 524.6±33.0 °C(Predicted) |
Appearance | Form solid, color White |
pKa | 14.85±0.20(Predicted) |
Storage Condition | -20°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Physical and Chemical Properties | Bioactive IDO-IN-2 (RG 6078, NLG-919 analog, GDC-0919 analog) is an effective IDO1 pathway inhibitor with IC50 value of 38 nM. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.541 ml | 17.707 ml | 35.413 ml |
5 mM | 0.708 ml | 3.541 ml | 7.083 ml |
10 mM | 0.354 ml | 1.771 ml | 3.541 ml |
5 mM | 0.071 ml | 0.354 ml | 0.708 ml |
Solubility | Soluble in DMSO (up to 15 mg/ml) |