NOE

NOE - Names and Identifiers

Name	2-Ethylaniline
Synonyms	NOE 2-Ethylaniline o-ethyl-anilin O-ETHYLANILINE 2-ethyl aniline Aniline, 2-ethyl- Aniline, o-ethyl- ORTHOETHYLANILINE 2-Ethylphenylamine 2-Ethylbenzeneamine OLEOYL ETHANOLAMIDE 2-ETHYLANILIN, 1 ML O-AMINOETHYLBENZENE N-OLEOYLETHANOLAMIDE Benzenamine, 2-ethyl- OLEIC MONOETHANOLAMIDE OLEIC ACID ETHANOLAMIDE
CAS	578-54-1
EINECS	209-424-2
InChI	InChI=1/C8H11N/c1-2-7-5-3-4-6-8(7)9/h3-6H,2,9H2,1H3
InChIKey	MLPVBIWIRCKMJV-UHFFFAOYSA-N

NOE - Physico-chemical Properties

Molecular Formula	C8H11N
Molar Mass	121.18
Density	0.983 g/mL at 25 °C (lit.)
Melting Point	-44 °C (lit.)
Boling Point	210 °C (lit.)
Flash Point	196°F
Water Solubility	insoluble
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0.11 mm Hg ( 20 °C)
Vapor Density	4.2 (vs air)
Appearance	Liquid
Color	Clear yellow to red-brownish
BRN	1841268
pKa	pK1:4.42(+1) (25°C)
Storage Condition	−20°C
Refractive Index	n20/D 1.559(lit.)
Physical and Chemical Properties	Melting Point -44°C boiling point 210°C(lit.) density 0.983g/mL at 25°C(lit.) vapor density 4.2 (vs air) vapor pressure 0.11mm Hg (20°C) refractive index n20/D 1.559(lit.) flash point 196 °F storage conditions − 20°C water-soluble insoluble BRN 1841268
Use	Is an important pesticide, dye and pharmaceutical intermediates, pesticide is a key intermediate for the synthesis of new pesticides

NOE - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R33 - Danger of cumulative effects R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S28A -
UN IDs	UN 2273 6.1/PG 3
WGK Germany	3
RTECS	BX9800000
FLUKA BRAND F CODES	8
TSCA	Yes
HS Code	29214980
Hazard Class	6.1
Packing Group	III

NOE - Nature

Open Data Verified Data

light yellow liquid, gradually darkened when exposed to sunlight. Melting Point -43 °c. Boiling Point 210~216 ℃,112~116 ℃ (3.333kPa), relative density 0. 982 (22 ℃). Refractive index 1.5584 (22 degrees C). Flash point 91 degrees Celsius. Soluble in water, ethanol.

Last Update：2024-01-02 23:10:35

NOE - Preparation Method

Open Data Verified Data

prepared by reduction of O-nitroethylbenzene.

iron powder reduction method using this method the raw material consumption per production of It product is: O-nitroethylbenzene (100%)1. 66t, ammonium chloride (industrial) 350kg, caustic soda 160kg, iron powder (industrial) 1.65t, salt (industrial) 1. 4T.
sodium sulfide reduction method sodium sulfide and O-nitroethylbenzene were reacted at 120~130 C, and the reaction mixture was separated to obtain the product, and the product yield was 95%.

Last Update：2022-01-01 10:51:05

NOE - Use

Open Data Verified Data

This product is a raw material for the synthesis of pre-seedling selective herbicide, trimethoprim and insecticide, ethyl chloramidine; It is also used for the manufacture of sulfurized fast blue dye and so on.

Last Update：2022-01-01 10:51:04

NOE - Safety

Open Data Verified Data

LD50 of this product is 1260mg/kg. Has a strong stimulating effect on the eyes. It is irritating to mucosa and upper respiratory tract. Inhalation can cause methemoglobinemia, cyanosis. Protection Measure see 2, 6-methylaniline.
packaging using small opening steel barrel, screw mouth glass bottle, cover pressure mouth glass bottle, plastic bottle or metal barrel (can) outside the wood box. Store in a cool, ventilated room. Keep away from fire and heat source. Storage period should not be too long, the provisions of a three-month rotation. Keep the container sealed. Should be stored separately from oxidants, acids, food chemicals. Handling should be light and light unloading, to prevent packaging and container damage.

Last Update：2022-01-01 10:51:05

NOE - Reference Information

LogP	1.74
NIST chemical information	Information provided by: webbook.nist.gov (external link)
EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
Use	After the N-alkylation reaction of o-ethylaniline and 2-bromopropane, the chloroacetic acid-phosphorus trichloride is directly acylated to produce oxalamine. This is a pre-seedling selective herbicide that has a good effect on the removal of gramineous weeds and certain broad-leaved weeds. O-ethylaniline is also the raw material of methoxamine and the insecticide ethyl chlordimeform. In the dye industry, this product can be used to make vulcanized sun-resistant blue. It is an important pesticide, dye and pharmaceutical intermediate. Pesticides are the key intermediates for the synthesis of new pesticides. Used in organic synthesis.
Production method	is obtained by reduction of o-nitroethylbenzene. 1. The raw material consumption of each 1t product produced by the iron powder reduction method is: 1.66t of o-nitroethylbenzene (100%), 350kg of ammonium chloride (industrial product), 160kg of caustic soda (100%), 1.65t of iron powder (industrial product) and 1.4t of refined salt (industrial product). 2. Sodium sulfide reduction method Sodium sulfide and o-nitroethylbenzene react at 120-130 ℃, and the reaction mixture is separated to obtain the product with 95% yield.
category	toxic substances
toxicity classification	poisoning
acute toxicity	oral-rat LD50: 1260 mg/kg; Oral-wild bird LD50: 750 mg/kg
flammability hazard characteristics	open flame is combustible; heated decomposition; combustion produces toxic nitrogen oxide smoke
storage and transportation characteristics	warehouse ventilation and low temperature drying; Store separately from oxidants, acids and food additives
fire extinguishing agent	dry powder, foam, carbon dioxide, sand
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)