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NSC 3426

6-methyl-1,2,4-triazine-3,5-diol

CAS: 932-53-6

Molecular Formula: C4H5N3O2

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NSC 3426 - Names and Identifiers

Name 6-methyl-1,2,4-triazine-3,5-diol
Synonyms NSC 3426
NSC 38620
AI3-50849
USAF CB-28
CCRIS 3440
Azathymine
6-AZATHYMINE
6-Azathymine
6-AZA-5-METHYLURACIL
5-Methyl-6-azauracil
6-METHYL-S-TRIAZINE-3,5-DIONE
6-Methyl-as-triazine-3,5-diol
6-methyl-1,2,4-triazine-3,5-diol
6-Methyl-1,2,4-triazine-3,5-diol
6-Methyl-1,2,4-triazine-3,5-dione
3,5-DIHYDROXY-6-METHYL-1,2,4-TRIAZINE
3,5-Dihydroxy-6-methyl-1,2,4-triazine
6-Methyl-as-triazine-3,5-(2H,4H)-dione
as-Triazine-3,5(2H,4H)-dione, 6-methyl-
6-AZA-2,4-DIHYDROXY-5-METHYL-PYRIMIDINE
6-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
6-Methyl-1,2,4-triazine-3,5(2H,4H)-dione
1,2,4-Triazine-3,5(2H,4H)-dione,6-methyl-
1,2,4-TRIAZINE-3,5(2H,4H)-DIONE, 6-METHYL-
1,2,4-Triazine-3,5(2H,4H)-dione, 6-methyl- (9CI)
CAS 932-53-6
EINECS 213-253-9
InChI InChI=1/C4H7N3O2/c1-2-3(8)5-4(9)7-6-2/h2,6H,1H3,(H2,5,7,8,9)
InChIKey XZWMZFQOHTWGQE-UHFFFAOYSA-N

NSC 3426 - Physico-chemical Properties

Molecular FormulaC4H5N3O2
Molar Mass127.1
Density1.4748 (rough estimate)
Melting Point210-212°C
Boling Point235.85°C (rough estimate)
Appearancepowder to crystal
ColorWhite to Almost white
Merck14,903
BRN126863
pKa7.6(at 25℃)
Storage Condition2-8℃
Refractive Index1.5000 (estimate)
MDLMFCD00006457
In vitro study 6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.
In vivo study The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5- 14 C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.

NSC 3426 - Risk and Safety

Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
RTECSXY8050000
Hazard ClassIRRITANT

NSC 3426 - Reference Information

biological activity 6-Azathymine, a 6-nitrogenous analog of thymine, it is a potent D-3-aminoisobutyrate-pyruvate aminotransferase (D-3-aminoisobutyrate-pyruvate aminotransferase) inhibitor. 6-Azathymine inhibits DNA biosynthesis and has antibacterial and antiviral activity.
Last Update：2024-04-09 21:54:55
NSC 3426
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CAS: 932-53-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: 6-Azathymine Visit Supplier Webpage Request for quotation
CAS: 932-53-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 6-Azathymine Visit Supplier Webpage Request for quotation
CAS: 932-53-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
NSC 3426
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屈西多巴
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