Nalpha-BOC-Nbeta-xanthenyl-L-asparagine

Nalpha-BOC-Nbeta-xanthenyl-L-asparagine - Names and Identifiers

Name	N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine
Synonyms	BOC-Asn(Xan)-OH N-Boc-N'-xanthyl-L-asparagine nα-boc-nβ-xanthenyl-l-asparagine N-α-t.-Boc-N-b-xanthyl-L-asparagine nα-boc-nγ-(9-xanthenyl)-l-asparagine na-T-boc-N-gamma-xanthyl-L-asparagine Nalpha-BOC-Nbeta-xanthenyl-L-asparagine N-ALPHA-(T-BOC)-N-BETA-XANTHENYL-L-ASPAR NALPHA-TERT-BOC-NGAMA-XANTHYL-L-ASPARAGINE N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine N-alpha-t-butyloxycabonyl-L-N-beta-xantyl-asparagine N-ALPHA-T-BUTYLOXYCARBONYL-L-N-BETA-XANTYL-ASPARAGINE NALPHA-tert-Butoxycarbonyl-NB-(9-xanthenyl)-L-asparagine N~2~-(tert-butoxycarbonyl)-N-9H-xanthen-9-yl-L-asparagine NALPHA-tert-Butoxycarbonyl-NGAMMA-(9-xanthenyl)-L-asparagine
CAS	65420-40-8
InChI	InChI=1/C22H24N2O6/c1-22(2,3)30-21(28)23-15(20(26)27)12-18(25)24-19-13-8-4-6-10-16(13)29-17-11-7-5-9-14(17)19/h4-11,15,19H,12H2,1-3H3,(H,23,28)(H,24,25)(H,26,27)/t15-/m0/s1

Nalpha-BOC-Nbeta-xanthenyl-L-asparagine - Physico-chemical Properties

Molecular Formula	C22H24N2O6
Molar Mass	412.44
Density	1.32±0.1 g/cm3(Predicted)
Melting Point	177.5-181.5°C(lit.)
Boling Point	650.7±55.0 °C(Predicted)
Flash Point	347.3°C
Vapor Presure	8.06E-18mmHg at 25°C
Appearance	Solid
Color	White to off-white
BRN	5172403
pKa	3.93±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.614

Nalpha-BOC-Nbeta-xanthenyl-L-asparagine - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29329990
Hazard Class	IRRITANT

Nalpha-BOC-Nbeta-xanthenyl-L-asparagine - Introduction

N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine is an organic compound widely used in the fields of biochemistry and medicinal chemistry. The following is a description of its nature, use, preparation and safety information:

Nature:
N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine is a crystalline solid. It has a white or yellowish color and is soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane. It is relatively stable at room temperature, but will decompose under high temperature or strong alkali conditions.

Use:
N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine has important application value in drug research. It can be used in the synthesis of peptide drugs, such as anti-tumor drugs and bioactive peptide precursor compounds. In addition, it can be used as a research tool in chemical biology to explore the structure and function of specific proteins or peptides.

Preparation Method:
The preparation of N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine generally involves a multi-step reaction. First, the first intermediate was obtained by the condensation reaction of synthetic aspartic acid-4, 4 '-diisopropylamino ester with p-aminobenzoic acid. A nucleophilic substitution reaction is then used to introduce the oxyanthryl nylon into the intermediate to form the final product.

Safety Information:
N(alpha)-boc-N(gamma)-(9-xanthenyl)-L-asparagine is an organic synthesis reagent, and its correct operation needs to follow general laboratory safety regulations. Due to the lack of complete data from toxicity studies of this compound, knowledge of its potential hazards is limited. During handling and use, care should be taken to avoid direct contact with the skin and eyes, and to avoid inhaling its powder or gas. To ensure safety, it is recommended to operate in the laboratory and use it in accordance with the regulations of personal protective equipment.

Last Update：2024-04-09 21:04:16