Nalpha-Cbz-L-Arginine
Nalpha-Carbobenzyloxy-L-arginine
CAS: 1234-35-1
Molecular Formula: C14H20N4O4
Nalpha-Cbz-L-Arginine - Names and Identifiers
| Name | Nalpha-Carbobenzyloxy-L-arginine |
| Synonyms | Z-Arg
Z-Arg-OH Z-L-Arg-OH Cbz-L-arginine Nα-Z-L-Arginine N(alpha)-Z-L-arginine Nalpha-CBZ-L-Arginine N(alpha)-Cbz-L-arginine BenzyloxycarbonylLarginine na-cbz-L-arginine free acid N2-Carbobenzyloxy-L-arginine N-2-carbobenzyloxy-L-arginine Na-Benzyloxycarbonyl-L-arginine Nalpha-Carbobenzyloxy-L-arginine NALPHA-Benzyloxycarbonyl-L-arginine n2-[(phenylmethoxy)carbonyl]-l-arginin N2-[(phenylmethoxy)carbonyl]-L-arginine N(alpha)-Benzyloxycarbonyl-L-arginine~Z-Arg-OH N~2~-[(benzyloxy)carbonyl]-N~5~-(diaminomethylidene)-L-ornithine |
| CAS | 1234-35-1 |
| EINECS | 214-973-6 |
| InChI | InChI=1/C14H20N4O4/c15-13(16)17-8-4-7-11(12(19)20)18-14(21)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,18,21)(H,19,20)(H4,15,16,17)/t11-/m0/s1 |
Nalpha-Cbz-L-Arginine - Physico-chemical Properties
| Molecular Formula | C14H20N4O4 |
| Molar Mass | 308.33 |
| Density | 1.1765 (rough estimate) |
| Melting Point | 171-174°C (dec.)(lit.) |
| Boling Point | 448.73°C (rough estimate) |
| Specific Rotation(α) | -11 º (c=0.5, 0.5N HCl 24 ºC) |
| Solubility | DMSO, Water |
| Appearance | White powder |
| Color | White |
| BRN | 2169267 |
| pKa | 3.90±0.21(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -10 ° (C=5.5, 0.2mol |
| MDL | MFCD00001762 |
Nalpha-Cbz-L-Arginine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29252900 |
Nalpha-Cbz-L-Arginine - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| overview | CBZ-L-arginine is mainly used in polypeptide synthesis. L-arginine has a wide range of uses and functions. In the prior art, Cbz is used as a protecting group to protect L-arginine. CBZ-L-arginine is an important intermediate raw material for many kinds of medicine and biotechnology. |
| preparation | 30.0g of sodium bicarbonate is suspended in 120 mL of water, 20.0g of arginine monohydrochloride is added, stirred, 20 mL of benzyloxycarbonyl chloride is added dropwise to the above system within 30 min, stirred for 8 h at room temperature, cooled and filtered at 4 ℃, diethyl ether and a small amount of cold water are washed and dried to obtain 26 .4g of white powder, the yield is 90. 2%, mp 174~177 ℃. |
| Application | N-benzyloxycarbonyl-L-arginine is an amino acid derivative that can be used for biochemical reagents and peptide synthesis. |
| use | used for biochemical reagents, peptide synthesis. |
Last Update：2024-04-09 20:52:54
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Mobile: 18021002903
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