Neocurzerene
Curzerene
CAS: 17910-09-7
Molecular Formula: C15H20O
Neocurzerene - Names and Identifiers
| Name | Curzerene |
| Synonyms | Curzerene Neocurzerene Isogermafuren Isogermafurene Isofuranogermacrene Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel- |
| CAS | 17910-09-7 |
Neocurzerene - Physico-chemical Properties
| Molecular Formula | C15H20O |
| Molar Mass | 216.32 |
| Density | 0.982±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 282.8±40.0℃ (760 Torr) |
| Specific Rotation(α) | (c, 0.87 in CHCl3)-0.7 |
| Flash Point | 117.5±14.2℃ |
| Appearance | oily liquid |
| Storage Condition | 2-8 ℃, stored with nitrogen |
| Physical and Chemical Properties | Colorless crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from zedoary. |
Neocurzerene - Reference
| Reference Show more | 1. Mai Haiyan, Huang Jiwei, Xiao Peiyu. Simultaneous Determination of Three Components in Yujin by Gas Chromatography [J]. Shi Zhen Guo Yi Guo Yao, 2013, 24(008):1894-1896. 2. Sun, Zhiming, et al. "Hydrothermal fabrication of rectorite based biocomposite modified by chitosan derived carbon nanoparticles as efficient mycotoxins adsorbents." Applied Clay Science 184 (2020): 105373.https://doi.org/10.1016/j.clay. 2019.105373 3. [IF=5.34] Pu Wu et al."Bioactivity-guided discovery of quality control markers in rhizomes of Curcuma wenyujin based on spectrum-effect relationship against human lung cancer cells."Phytomedicine. 2021 Jun;86:153559 |
Neocurzerene - Reference Information
| Overview | Curcumfurane is an organic heterocyclic compound with anti-tumor effects and can be used to prepare pharmaceutical compositions. |
| Biological activity | Curzerene are sesquiterpenes, isolated from the rhizomes of Curculigo orchioides Gaertn, and have anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces apoptosis (apoptosis). |
| target | GSTA1 |
| Cell Line: | SPC-A1 cells SPC-A1 cells SPC-A1 cells SPC-A1 cells |
| Concentration: | 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM 0 µM, 6.25 µM, 12.5 µM, 25 µM, 50 µM, 100 µM 6.25 µM, 25 µM, 100 µM |
| Incubation Time: | 24 hours, 48 hours, 72 hours 48 hours 48 hours 48 hours |
| Result: | Inhibited growth of non-small cell lung cancer SPC A1 cells in vitro. Induced apoptosis of the cells in a dose-dependent manner. Induced G2/M cell cycle arrest of SPC A1 cells. Decreased GSTA1 mRNA expression. |
| use | zedoary turmerene has the function of promoting qi and breaking blood, eliminating accumulation and relieving pain. Used for the role of early cervical cancer. |
Last Update：2024-04-09 21:11:58
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Multiple SpecificationsSpot supply
Product Name: Curzerene Visit Supplier Webpage Request for quotationCAS: 17910-09-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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